There has been much research effort in the development of an accurate and reliable threedimensional dose verification system, prompted by the advances of technologies in radiation treatment of cancer patients. New radiotherapy techniques such as intensity modulated radiation therapy (IMRT), stereotactic radiosurgery (SRS) and high dose rate (HDR) brachytherapy are aimed at dose deliveries that ...

Background: Radiation-sensitive polymer gels are among the most promising three-dimensional dose verification tools and tissue-like developed to date. Among the special features of this type of dosimeters, is be doped with other elements or chemicals which made them appropriate for investigating of dose enhancement with contrast agents, by high atomic number. Material and Methods: In this study...

Abstract. Gel dosimeters are integrating dosimeters, that enable dose verification in three dimensions. Optical analysis of gel dosimeters has demonstrated to be an available technique for imaging the absorbed in-phantom dose exposed to radiotherapy beams. The goal is to demonstrate the ability of gel dosimeters to achieve accurately and spatial resolution in dose mapping, also when high dose r...

Introduction: Multiple fields and presence of heterogeneities create complex dose distributions that need three dimensional dosimetry. In this work, we investigated MR-based MAGIC gel dosimetry as a three-dimensional dosimetry technique to measure the delivered dose to bladder and rectum in prostate radiation therapy. Materials and Methods: A heterogeneous slab phantom including bones was made....

Introduction: Currently, the potential application of gold nanoparticles (AuNPs) to increase the efficiency of radiation therapy have been investigated. However, the loss of an appropriate method to estimate the dose distribution in nanoparticle laden tissue limits the applicability of nanoparticles in radiotherapy clinics. Polymer gel dosimetry provides an accurate and precise...

Introduction: The purpose of the current study was to investigate the effect of X-ray spectra on the sensitivity of a polymer gel dosimeter imaged with a conventional computed tomography (CT) scanner. Material and Methods: The whole process of CT imaging of an irradiated polymer gel was simulated by MCNPX Monte Carlo (MC) code. The imaging of polyacrylamide gel was accomplished by means of a co...

Introduction Polymer gel dosimeters offer a practical solution to 3D dose verification for conventional radiotherapy as well as intensity-modulated and stereotactic radiotherapy. In this study, EGSnrc calculated and PAGAT polymer gel dosimeter measured dose profiles from single shot irradiation with 18 mm collimator of Gamma Knife in homogeneous and inhomogeneous phantoms were compared with eac...

In this work we use a 3D quantitative CT imaging ultrasound system to characterise polymer gel dosimeters. The system comprises of two identical 5 MHz 128 element phasedarray ultrasound transducers co-axially aligned and submerged in water as a coupling agent. Rotational and translational movement of the gel dosimeter sample between the transducers were performed using a robotic arm. Ultrasound...