• Anti-lysozyme DNA aptamer (Apt) was immobilised on L -cysteine ZnSSe quantum dots (QDs). Plasmonic gold nanoparticles (AuNPs) were bonded to the Apt-ZnSSe QDs. Lysozyme quantitatively detected by QDs-AuNPs biosensor probe. The highly selective against tested enzymes. successfully in human saliva. We report construction of an (Apt)-based fluorescent platform for salivary lysozyme using plasmon...

First, the relationship between factor analysis (FA) and the well-known arbitrage pricing theory (APT) for financial market is discussed comparatively, with a number of to-be-improved problems listed. An overview is made from a unified perspective on the related studies in the literatures of statistics, control theory, signal processing, and neural networks. Next, we introduce the fundamentals ...

An internal segment of the (p)ppGpp synthetase gene, relA, of Streptomyces coelicolor A3(2) was amplified from genomic DNA using the polymerase chain reaction and used as a hybridization probe to isolate the complete gene from a cosmid library. relA lies downstream of a gene (apt) that apparently encodes adenine phosphoribosyltransferase and is transcribed from two promoters, relAp1 and relAp2,...

This article investigates the structure onpreferences required to derive Ross’s arbitrage pricing theory (APT). It is shown that only ordinalpreferences are required. In particular, the APT does not require that agents possess preferences representable as riskaverse expected utility functions. This characteristic of the APT is not shared by the standard equilibriumbased capital asset pricing mo...

There is strong evidence to suggest that happy hour drink specials are associated with undesirable outcomes such as increased amount of drinking, increased likelihood of being highly intoxicated, and increased likelihood of experiencing negative outcomes related to drinking (e.g., getting into fights). Public policy efforts have been made to ban or at least restrict alcohol drink specials. Rese...

Since the infancy of microscopy and surface science, many advanced techniques have been utilized to better understand catalytic systems. Previous studies focus either on the catalytic reaction (reactivity and selectivity) or on the catalyst itself, focusing on structural/morphological reconstructions as well as changes in the chemical composition of the catalyst. Atom probe tomography (APT) is ...

To improve the efficacy of drug delivery, active targeted nanotechnology-based drug delivery systems are gaining considerable attention as they have the potential to reduce side effects, minimize toxicity, and improve efficacy of anticancer treatment. In this work CUR-NPs (curcumin-loaded lipid-polymer-lecithin hybrid nanoparticles) were synthesized and functionalized with ribonucleic acid (RNA...

In this paper we propose Block Device Layer with Automatic Parallelism Tuning (BDL-APT), a mechanism that maximizes the goodput of heterogeneous IP-based Storage Area Network (IP-SAN) protocols in long-fat networks. BDL-APT parallelizes data transfer using multiple IP-SAN sessions at a block device layer on an IP-SAN client, automatically optimizing the number of active IP-SAN sessions accordin...

Mucin 1 (MUC1) is an important molecular target for cancer treatment because it is overexpressed in most adenocarcinomas. In this study, a new MUC1-targeted drug delivery system was assembled using an aptamer (Apt) that could recognize MUC1 and a DNA tetrahedron (Td) that could carry doxorubicin (Dox) within its DNA structure. The complex thus formed (Apt-Td) had an average size of 12.38 nm and...

Amide proton transfer (APT) imaging is a novel MRI technique, in which the amide protons of endogenous proteins and peptides are irradiated to accomplish indirect detection using the bulk water signal. In this paper, the APT approach was added to a standard brain MRI protocol at 3T, and twelve patients with high-grade gliomas confirmed by histopathology were scanned. It is shown that all tumors...