We report a patient with X-linked lymphoproliferative disease (XLP) who developed multiple central nervous system (CNS) manifestations of Epstein-Barr virus infection. XLP, or Duncan syndrome, is a rare inherited disorder characterized by the inability to clear Epstein-Barr virus infection. In addition to Epstein-Barr virus encephalitis, CNS lymphoproliferative disease, and lymphoma, this patie...

Lymphoproliferative disorders following liver transplantation are often Epstein-Barr virus (EBV)-related highgrade B cell lymphomas. EBV-negative and low-grade lymphoma is a very rare condition after cadaveric as well as living donor liver transplantation (LDLT). Herein we report a case of follicular lymphoma with negative EBV viral capsid antigen (VCA), IgM, IgG and Epstein-Barr virus-encoded ...

Guideline update and changes: This guideline is an updated version of the 2008 guideline, revised to take into account the 2008 WHO guidelines as they apply to the lymphoproliferative disorders. There have been no changes to the sections on histiocytic and dendritic cell neoplasms. The pathology of posttransplant lymphoproliferative disorder is dealt with in the BCSH guideline on this topic. Th...