Robust and modular systems for T cell expansion have immense utilities clinical development immunoengineering research. In article 2101190, Che-Ming J. Hu co-workers demonstrate a photoactivated intracellular radical polymerization technique that transforms live dendritic cells into functional T-cell-stimulating biomaterial, which effectively enhances adoptive therapy against cancer in mice.

objective: dendritic cells (dcs) play a critical role in the beginning and in the course of immune responses. by observing. considering the defect in these cells in patients with tumor malignancy. in recent years there has been considerable interests in correction and use of these cells. in our prvious studies we showed that lysate of listeria monocytogenese can induce maturation of dendritic c...

Dendritic cells are present in both lymphoid and non-lymphoid organs, which heterogenous group of nonphagocytic nonlymphoid immune accessory cells. Plasmacytoid dendritic cell (which has an eccentric nuclei) subset aid secreting high levels type 1 interferons by activation gaining like morphology, play important role antiviral immunity involved initiation development stages inflammatory respons...