While recent reports have commented on the elevated ambient levels of hazardous air pollutants (HAPs) in certain areas of Houston, relative to other cities, few studies have assessed the health effects of HAPs for Houstonians and none have evaluated the association between ambient levels of these pollutants and lymphohematopoietic cancer risk in this population. To begin to address this deficit...

CD34 is highly glycosylated surface antigen of enormous clinical utility in the identification, enumeration, and purification of engraftable lymphohematopoietic progenitors for transplantation. However, recently its importance in the specific marking of most immature hematopoietic stem/progenitor cells have been questioned by addressing long-term reconstitution capability of CD34(-) hematopoiet...

After successful bone marrow transplantation, patient hematopoietic and lymphoid cells are replaced by cells derived from the donor marrow. To document and characterize successful engraftment, host and donor cells must be distinguished from each other. We have used DNA sequence polymorphism analysis to determine reliably the host or donor origin of posttransplant cell populations. Using a selec...

Data from many laboratory and clinical investigations indicate that CD34+ cells comprise approximately 1% of human bone marrow (BM) mononuclear cells, including the progenitor cells of all the lymphohematopoietic lineages and lymphohematopoietic stem cells (stem cells). Because stem cells are an important but rare cell type in the CD34+ cell population, investigators have subdivided the CD34+ c...

female cancer, especially breast and gynecologic cancers are considered multistage disease, highly influenced by risk and protective factors and/or screening preventive modalities. consequences of all these factors result in the trend of change over time.in this comparative study, based on data of national cancer registry of iran 2004 published by iranian ministry of health, age - standard inci...

introduction: allogeneic hematopoietic stem cell transplantation is a potentially curative treatment modality for hematological malignancies. we evaluated the outcome of patients suffering from hematological malignancies, including acute leukemias, chronic myeloid leukemia and myelodysplastic syndrome after allogeneic transplantation. methods: all patients having hematological malignancies with...

The hematopoietic syndrome is anticipated when a dose of radiation greater than 100 cGy is received. The resulting clinical situation is life-threatening because of opportunistic infections and gradual decline in immune competency due to irradiation. Because of evidence of a possible immunomodulatory role for cimetidine, an antagonist of histamine H2 receptors, we studied the effects of thi...

the hematopoietic syndrome is anticipated when a dose of radiation greater than 100 cgy is received. the resulting clinical situation is life-threatening because of opportunistic infections and gradual decline in immune competency due to irradiation. because of evidence of a possible immunomodulatory role for cimetidine, an antagonist of histamine h2 receptors, we studied the effects of this dr...