Indrani Dhawan 1 , Oneal Gupta 1 , Ankit Kaushik* 1 , Sunil Ranga 1 , Dimple Kasana 2 , Prem R Gupta 1 1 Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India 2 Department of Microbiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India Background: Tuberculosis (TB) is the leading cause of death from a curable infectious d...

A total of 43 episodes of tuberculosis lymphadenitis were treated in 32 adult patients. In 12 instances the affected lymph node was excised without any chemotherapy; there were 10 relapses. The treatment was local excision of the affected lymph nodes together with antituberculosis chemotherapy with at least two drugs in 30 instances; there were no relapses following such therapy.Presumably pati...

In this review, representative types of granulomatous lymphadenitis (GLA) are described. GLA can be classified as noninfectious GLA and infectious GLA. Noninfectious GLA includes sarcoidosis and sarcoid-like reaction. The cause of sarcoidosis remains unknown, but it has good prognosis. Sarcoid-like reaction, which is considered to be a biological defense mechanism, is observed in regional lymph...

Mediastinal lymphadenopathy in patients with malignancy may not be always metastatic disease. We present three patients with proven thoracic or extra thoracic malignancies with mediastinal lymphadenopathy which were subsequently proven as granulomatous lymphadenitis by endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA). The objective of the current report is to emphasi...

Cat scratch disease is a non-epidemic infection caused by Gram negative bacillus Bartonella henselae. The most common course of the disease includes regional lymphadenitis and skin papule at the entrance site of the infection. We report a case of a female, 22 years of age, with cat scratch disease. Clinically we observed the typical skin papule at the entrance site of the infection with severe ...

In three pediatric patients with necrotizing lymphadenitis, cytosol aminopeptidase activity (c-AP; EC 3.4.11.1) in serum was markedly increased to 509, 417, and 191 U/L, respectively (normal range 25-60 U/L). Lactate dehydrogenase (LD; EC 1.1.1.27) was also increased, with LD-3 predominating. The increased concentrations of c-AP and LD presumably originated from the destruction of infected, act...

Histiocytic necrotising lymphadenitis is the pathognomonic histological appearance of lymph nodes in Kikuchi's disease, a condition characterised by a brief systemic illness and lymphadenopathy. The case is described of a young man, originally diagnosed as having Kikuchi's disease by lymph node histology, who subsequently developed systemic lupus erythematosus with symmetrical polyarthritis, Co...