Lupus vulgaris, a common form of cutaneous tuberculosis, usuallyhas different patterns including the plaque form, ulcerative andmutilating form, vegetative form, tumor-like form, and papularand nodular form. Lupus vulgaris commonly appears on thenormal skin as a solitary lesion. However, certain uncommonforms are identified that pose a diagnostic dilemma. Sporotrichoidlikespread has been rarely...

Lupus erythematosus, especially the discoid form, and lichen planopilaris may be associated and can occur in different topographies (coexistence) or in the same lesion (lupus eythematosus/lichen planus overlap syndrome). Frontal fibrosing alopecia is considered a variant form of lichen Received: October 24, 2016 Accepted: October 27, 2016 Published online: November 12, 2016 Leandro Noriega Derm...

the neuropsychiatric manifestations of systemic lupus erythematosus are frequent. one of the most serious presentations is convulsion. this study was carried out to evaluate the relation between convulsion and anti-dna antibody levels. an analytic, retrospective case-controlled study was carried out, with reference to 1001 recorded cases of systemic sle lupus erythematosus in lupus unit, rheuma...

Objective(s):Genetic and environmental factors are involved in the pathogenesis of systemic lupus erythematosus (SLE). Autoreactive lymphocytes are cleared through apoptosis and any disturbance in the apoptosis or clearance of apoptotic cells may disturb tolerance and lead to autoimmunity. Vitamin D has anti-proliferative effects and controls cell cycle progression. In this study we investigate...

Efficacy of plasma exchange in patients with systemic lupus erythematosus has not been supported by the results of the first non-controlled and retrospective studies. Nonetheless, they remain relevant for some selected patients with life-threatening manifestations and/or severe therapy-resistant manifestations. They can be used as an adjuvant therapy in combination with corticosteroids and, whe...

Serum from patients with systemic lupus erythematosus (SLE) prevents the proliferative response of normal T cells when stimulated by autologous or allogeneic non-T cells. The abrogation of proliferation in an autologous mixed lymphocyte reaction (AMLR) with SLE serum is associated with a lack of suppressor T cell generation. Fractionation of SLE sera on sucrose gradients reveals an 18-12 S peak...

Lupus erythematosus, especially the discoid form, and lichen planopilaris may be associated and can occur in different topographies (coexistence) or in the same lesion (lupus eythematosus/lichen planus overlap syndrome). Frontal fibrosing alopecia is considered a variant form of lichen Received: October 24, 2016 Accepted: October 27, 2016 Published online: November 12, 2016 Leandro Noriega Derm...

  Objective(s): Lupus nephritis (LN) is the main cause of mortality and disability in systemic lupus erythematosus (SLE) patients. Therefore, utilizing a reliable and non-invasive method for serial measurements of renal function seems to be necessary. The aim of this study was to evaluate the role of urinary lipocalin-2 as a biomarker of renal involvement in SLE patients.   Materi...

an 11-year-old female patient with autoimmune hepatitis (aih) was referred to our rheumatology clinic due to her current musculoskeletal manifestations. the patient had been diagnosed with aih 3 months previously, based on jaundice and impaired liver function tests, and she had been treated with low-dose prednisolone and azathioprine. she presented with malaise, arthritis, a malar rash on the f...