Oxidized modifications of LDL (oxLDL) play a key role in the development of endothelial dysfunction and atherosclerosis. However, the underlying mechanisms of oxLDL-mediated cellular behavior are not completely understood. Here, we compared the effects of two major types of oxLDL, copper-oxidized LDL (Cu2+-oxLDL) and lipoxygenase-oxidized LDL (LPO-oxLDL), on proliferation of human aortic endoth...

This study aimed to calculate and compare the estimated organ absorption dose, risk of cancer due exposure, dose received by gonads for women men in radio diagnostic examinations with different projections. Radiographic examination abdomen (with anterior-posterior (AP) posterior-anterior (PA) projections) lumbar vertebrae projection (AP), Right oblique (RPO), Left (LPO)), were performed. Softwa...

A method has been developed to deliver an idoinating system into the confines of the phagolysosome, allowing us to study the nature of the phagolysosomal membrane. Lactoperoxidase (LPO) is covalently coupled to carboxylated latex spheres (LPO-latex) in a stable, enzymatically active form. The addition of LPO-latex to cultured macrophages leads to their rapid attachment, ingestion, and enclosure...

Free radicals, hydroxyperoxides and H(2)O(2) are all known to damage cell components. This study was designed to compare the concentrations of hydroxyperoxide and free radical scavengers in the cardiac muscles of old rats in the hyper- or hypothyroid condition, to determine whether rates of peroxidation would differ with age, thyroid status, or both. Rats were rendered hyper- or hypothyroid by ...

BACKGROUND Bacterial meningitis is often associated with cerebral compromise which may be responsible for neurological sequelae in nearly half of the survivors. Little is known about the mechanisms of CNS involvement in bacterial meningitis. Several studies have provided substantial evidence for the key role of nitric oxide (NO) and reactive oxygen species in the complex pathophysiology of bact...

Study was undertaken to investigate the various oxidative stress markers and biochemical parameters in anxious rat. Rats were subjected for short (21 days) and long term (up to 84 days) social isolation; the rats displayed an increase in anxiety on elevated plus maze and open field test relative to control. Various markers of oxidative stress like lipid peroxidation (LPO), reduced glutathione (...

The constructive study of metric spaces requires at first an examination of each classical proposition for numerical content. In classical mathematics it is a theorem that sequences in a compact space have convergent subsequences, but this is not constructively true. For compact intervals on the real line it has long been known that this theorem is nonconstructive because it implies the Limited...

Background Infertility is a problem concerning 10-15% of the individuals in the fertile period. This study investigated effects of proinflammatory factors as well as lipid hydroperoxides (LPO) levels upon in vitro fertilization (IVF) success. MaterialsAndMethods In this prospective, non-randomized, controlled clinical study, sera obtained from 26 fertile (group-1), 26 infertile women before (gr...