Results: Sixty participants (82%) in the low-fat group and 59 (79%) in the low-carbohydrate group completed the intervention. At 12 months, participants on the low-carbohydrate diet had greater decreases in weight (mean difference in change, "3.5 kg [95% CI, "5.6 to "1.4 kg]; P # 0.002), fat mass (mean difference in change, "1.5% [CI, "2.6% to "0.4%]; P # 0.011), ratio of total–high-density lip...

to the editor: The studies by Samaha et al. 1 and Foster et al. 2 (May 22 issue) are intended to expand our knowledge about low-carbohydrate diets. One potential long-term concern about the low-carbohydrate diet is its relatively high protein load and the effect this has on kidneys. This issue is especially important in persons with diabetes, who are more likely than others to have an underlyin...

To examine how a low-carbohydrate diet affects cognitive performance, women participated in one of two weight-loss diet regimens. Participants self-selected a low-carbohydrate (n=9) or a reduced-calorie balanced diet similar to that recommended by the American Dietetic Association (ADA diet) (n=10). Seventy-two hours before beginning their diets and then 48 h, 1, 2, and 3 weeks after starting, ...

BACKGROUND The optimal source and amount of dietary carbohydrate for managing type 2 diabetes (T2DM) are unknown. OBJECTIVE We aimed to compare the effects of altering the glycemic index or the amount of carbohydrate on glycated hemoglobin (HbA1c), plasma glucose, lipids, and C-reactive protein (CRP) in T2DM patients. DESIGN Subjects with T2DM managed by diet alone (n=162) were randomly ass...