Spontaneous intestinal perforations are localized perforations without the typical clinical, radiological, and histopathological features of necrotizing enterocolitis. Spontaneous intestinal perforation is a recently defined clinical entity. The best-known risk factor is prematurity. It is seen 2-3% in very low birthweight infants and 5 % of extremely low birthweight infants. Herein we report a...

OBJECTIVES This study examined whether the decline in birth-weight with increasing altitude is due to an independent effect of altitude or an exacerbation of other risk factors. METHODS Maternal, paternal, and infant characteristics were obtained from 3836 Colorado birth certificates from 1989 through 1991. Average altitude of residence for each county was determined. RESULTS None of the ch...

A range of health effects, including adverse pregnancy outcomes, have been associated with exposure to ambient concentrations of particulate matter (PM) and ozone (O3). The objective of this study was to determine whether maternal exposure to fine particulate matter (PM2.5) and O3 during pregnancy is associated with the risk of term low birthweight and small for gestational age infants in both ...

Evidence suggests that risk of chronic diseases may be programmed during the foetal and early life of the infant. With high rates of low birthweight coupled with a rapid nutritional transition, low-income countries are facing an epidemic of chronic diseases. Follow-up of a cohort of adults born during 1964-1978 in an urban slum in Lahore, Pakistan, is presented in this paper. In 695 of these ad...

Studies indicate that low birthweight (LBW) children display reduced deciduous tooth size but there is little information about permanent tooth size. It has also been shown that dental fluctuating asymmetry (FA) increases in response to various environmental influences, but the relationship between birthweight and FA remains unclear. The aim of this study was to compare tooth size and asymmetry...

OBJECTIVE To examine sex differences in birthweight-lipid associations. METHODS AND RESULTS Using prospectively collected data on birthweight and non-fasting lipid levels at age 44-45 y from the 1958 British birth cohort (3603 men and 3583 women), sex differences in birthweight-lipid associations were examined. There were inverse associations between birthweight and total and low-density-lipo...

In recent years, neonatal mortality rates for low-birthweight infants have declined both in neonatal intensive care units and in several populations in the industrialized world. With regard to impairment among surviving low-birthweight infants, studies from newborn intensive care units show considerable variation in the reported rates of handicaps. Much of this variation arises from a lack of u...

Newly-available data from the perinatal reporting system are used to examine the variation across socio-economic groups in perinatal mortality and low birthweight rates in Ireland. The results show significant effects of socio-economic background, mother's age and parity (number of previous births) on both perinatal mortality and low birthweight. The risk of perinatal mortality is highest where...

A population based cohort of 144 children weighing less than 2000 g who were without major handicap, and a random control sample of 163 children born at term and weighing over 3000 g were investigated. The aim was to assess the relative importance for cognitive development at 5 years of age, of birthweight, parental demographic factors, and factors related to the environment in which the child ...

AIM To monitor the trends in prevalence of cerebral palsy (CP) by birthweight in Europe, 1980 to 2003. METHOD Data were collated from 20 population-based registers contributing to the Surveillance of Cerebral Palsy in Europe database. Trend analyses were conducted in four birthweight groups: <1000g (extremely low birthweight [ELBW]); 1000 to 1499g (very low birthweight [VLBW]); 1500 to 2499g ...