نتایج جستجو برای: longevity

تعداد نتایج: 18074  

Journal: :journal of ornamental plants 2015
azam ranjbar noorollah ahmadi maliheh eftekhari

carnation (dianthus caryophyllus l.) is one of the most important cut flowers in the world. themajority of thecarnation cultivars are sensitive to ethylene which affected the physiological and biochemical postharvest characteristics of these flowers.applying inhibitors of biosynthesis and action of ethylene is important factor to protect the display quality and extend postharvest life. in order...

Journal: :Mechanisms of ageing and development 2003
Robert N Butler Steven N Austad Nir Barzilai Andreas Braun Stephen Helfand Pamela L Larsen Anna M McCormick Thomas T Perls Alan R Shuldiner Richard L Sprott Huber R Warner

Recent results indicate that the longevity of both invertebrates and vertebrates can be altered through genetic manipulation and pharmacological intervention. Most of these interventions involve alterations of one or more of the following: insulin/IGF-I signaling pathway, caloric intake, stress resistance and nuclear structure. How longevity regulation relates to aging per se is less clear, but...

2012
Robi Tacutu David E. Shore Arie Budovsky João Pedro de Magalhães Gary Ruvkun Vadim E. Fraifeld Sean P. Curran

Intricate and interconnected pathways modulate longevity, but screens to identify the components of these pathways have not been saturating. Because biological processes are often executed by protein complexes and fine-tuned by regulatory factors, the first-order protein-protein interactors of known longevity genes are likely to participate in the regulation of longevity. Data-rich maps of prot...

2013
Vanessa Gonzalez-Covarrubias Marian Beekman Hae-Won Uh Adrie Dane Jorne Troost Iryna Paliukhovich Frans M Kloet Jeanine Houwing-Duistermaat Rob J Vreeken Thomas Hankemeier Eline P Slagboom

Middle-aged offspring of nonagenarians, as compared to their spouses (controls), show a favorable lipid metabolism marked by larger LDL particle size in men and lower total triglyceride levels in women. To investigate which specific lipids associate with familial longevity, we explore the plasma lipidome by measuring 128 lipid species using liquid chromatography coupled to mass spectrometry in ...

2010
Andrés R. Schwember Kent J. Bradford

Lettuce (Lactuca sativa L.) seeds have poor shelf life and exhibit thermoinhibition (fail to germinate) above ∼25°C. Seed priming (controlled hydration followed by drying) alleviates thermoinhibition by increasing the maximum germination temperature, but reduces lettuce seed longevity. Controlled deterioration (CD) or accelerated ageing storage conditions (i.e. elevated temperature and relative...

2016
Marian Beekman Hae-Won Uh Diana van Heemst Manfred Wuhrer L. Renee Ruhaak Vanessa Gonzalez-Covarrubias Thomas Hankemeier Jeanine J. Houwing-Duistermaat P. Eline Slagboom

BACKGROUND In older people, chronological age may not be the best predictor of residual lifespan and mortality, because with age the heterogeneity in health is increasing. Biomarkers for biological age and residual lifespan are being developed to predict disease and mortality better at an individual level than chronological age. In the current paper, we aim to classify a group of older people i...

Journal: :Journal of biochemistry 2011
Sakiko Honjoh Eisuke Nishida

Traditionally, ageing has been considered a passive and entropic process, in which damages accumulate on biological macromolecules over time and the accumulated damages lead to a decline in overall physiological functions. However, the discovery of a longevity mutant in the nematode Caenorhabditis elegans has challenged this view. A longevity mutant is a mutant organism, in which a reduction-of...

2004
Byung Mook Weon

Accurate demographic functions help scientists define and understand longevity. We summarize a new demographic model, the Weon model, and show the application to the demographic data for Switzerland (1876-2002). Particularly, the Weon model simply defines the maximum longevity, which is induced in nature by the mortality dynamics. In this study, we reconsider the definition of the maximum longe...

Journal: :Proceedings. Biological sciences 2007
Paul E Eady Leticia Hamilton Ruth E Lyons

Antagonistic sexual coevolution stems from the notion that male and female interests over reproduction are in conflict. Such conflicts appear to be particularly obvious when male genital armature inflicts damage to the female reproductive tract resulting in reduced female longevity. However, studies of mating frequency, genital damage and female longevity are difficult to interpret because fema...

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