When transferring tissue regenerative strategies involving skeletal stem cells to human application, consideration needs to be given to factors that may affect the function of the cells that are transferred. Local anaesthetics are frequently used during surgical procedures, either administered directly into the operative site or infiltrated subcutaneously around the wound. The aim of this study...

Intraperitoneal administration of analgesia: is this practice of any utility? Local anaesthetic techniques are part of the multimodal approach to postoperative pain management. 1 This involves the use of opioids, non-steroidal anti-in¯ammatory drugs (NSAIDs) 2 , paracetamol 3 and local anaesthetics. 4 The purpose of this editorial is to review whether or not instillation of local anaesthetics i...

To evaluate the effect of adding midazolam to bupivacaine to prolong the analgesia characteristics of brachial plexus block. After preanaesthetic assessment all the patients were premedicated with diazepam 0.1mg/kg orally one hour before the surgery. Patients were randomly divided into group1 & 2. Group -1 patients received supraclavicular brachial plexus block with 30ml of 0.5% bupivacaine & g...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 1. Essential Physicochemical Properties of Local Anaesthetics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 2. Overview of the Toxic Effects of Local Anaesthetics . . . . . . . . . . . . . . . . . ...