background epilepsy is a chronic neurological disease with the prevalence of around one percent. despite the introductions of several anti-epileptic drugs, around 1/3 of epileptic patients are resistant to the anti-epileptic medications. objectives considering the evidence regarding the anti-oxidant action of vitamin e and its beneficiary effect in the treatment of epilepsy, we investigated the...

introduction: kainic acid (ka) induces neuropathological changes in specific regions of the mouse hippocampus comparable to changes seen in patients with chronic temporal lobe epilepsy (tle). according to different studies, the expression of a number of genes are altered in the adult rat hippocampus after status epilepticus (se) induced by ka. this study aimed to quantitatively evaluate changes...

background: this study compares the clinical characteristics of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) with those who have temporal lobe epilepsy (tle) due to other etiologies.   methods : in this retrospective study all patients with a clinical diagnosis of tle were recruited in a referral outpatient epilepsy clinic at shiraz university of medical scie...

We have performed complementary time-resolved fluorescence resonance energy transfer (TR-FRET) experiments and molecular dynamics (MD) simulations to elucidate structural changes in the phosphorylation domain (PD) of smooth muscle regulatory light chain (RLC) bound to myosin. PD is absent in crystal structures, leaving uncertainty about the mechanism of regulation. Donor-acceptor pairs of probe...

HPLC characterization of tilapia pituitary endorphins using an antibody specific for N-terminally acetylated endorphins yielded three major peaks in the neurointermediate lobe, but none in the pars distalis. The melanotropes secreted two of the immunoreactive products in vitro, one of which coeluted with Xenopus laevis N-ac-beta-END(1-8). This immunoreactive fraction also coeluted with diacetyl...

Membrane-associated peptidylglycine a-amidating monooxygenase (PAM) activity was investigated in rat anterior and neurointermediate pituitary tissues and in pituitary AtT-20p-16~ and GH, cell lines. A substantial fraction of total pituitary PAM activity was found to be membrane-associated. Triton X-100, Noctyl-8-D-glucopyranoside, and Zwittergent were effective in solubilizing PAM activity fr...

recently a new structure called groove gap waveguide (GGW) is ‎introduced to implement low loss microwave component devices ‎especially for millimeter wave applications. This paper presents a ‎new type of H-plane horn antenna making use of this new technology ‎in which backward radiation is significantly suppressed by ‎introducing a high impedance surface at the antenna aperture. The ‎high impe...

Dynamic modification of the pattern a reflector antenna system traditionally requires an array feeds. This paper presents alternative approach in which scattering from fraction around rim is passively modified using, for example, electronically-reconfigurable reflectarray. facilitates flexible sidelobe modification, including canceling, systems employing single feed. Applications such include r...

The region surrounding the reconnection separatrix consists of many particle and wave transient features (electron, cold hot ion beams, Hall E&B fields, kinetic Alfvén, LH, etc. waves) whose pattern parameters may vary depending on distance from active neutral line. We study nine quick MMS entries into plasma sheet boundary layer (PSBL) tail lobe to address meso-scale other characteristics phen...