BACKGROUND Nonalcoholic fatty liver disease, the hepatic manifestation of metabolic syndrome, is associated with increased risk of colorectal adenoma, a precursor of colorectal cancer. Because nonalcoholic fatty liver disease and colorectal adenoma share many common risk factors of metabolic syndrome, the association between these 2 pathological findings has been investigated in multiple studie...

Dysplastic nodules are premalignant neoplastic nodules found in explanted livers with cirrhosis. Genetic signatures of premalignant dysplastic nodules (DNs) with concurrent hepatocellular carcinoma (HCC) may provide an insight in the molecular evolution of hepatocellular carcinogenesis. We analyzed four patients with multifocal nodular lesions and cirrhotic background by whole-exome sequencing ...

the aim of this study was to analyze the stress response during 3 hours net confinement stress and recovery period of 22 hours in normal (std) and in 17α-hydroxylase deficient common carp (e5). fish were raised for 6 months and sampled at t0 (control, unstressed), 5 minutes, 20 minutes, 1 hour and 3 hours of exposure to net confinement, and after 1 hour, 4 hours, and 22 hours of recovery. at ev...

background: heroin as opium is being used in two pure and impure forms with known disastrous effects on different body organs including genital system. the aim of this study was to determine the changes in testosterone secretion, the percentage of fertility, changes of the body and testis weight, and gonado somatic index in mice (ballb/c). materials and methods: a total of 90 adult male and fem...

aim : the aim of this study was to review cases of non-alcoholic fatty liver disease (nafld) cases and to determine the prevalence of non-alcoholic fatty liver disease as a cause of elevated alanine aminotransferase (alt) in healthy blood donors in the permian area and also assess risk factors of nafld such as body mass index (bmi) and correlation with metabolic syndrome in these subjects. back...

Increases in milk yield from genetic selection may be accompanied by correlated increases in genetic susceptibility to clinical mastitis and somatic cells. Unlike clinical mastitis, somatic cell scores can be easily determined and recorded and are related to milk loss from subclinical mastitis. Selection against high somatic cell scores should decrease incidence of clinical mastitis and provide...

background non-alcoholic fatty liver disease (nafld) is a common liver disease in the western population and expanding disease in the world. pathological changes in fatty liver are like alcohol liver damage, which can lead to end-stage liver disease. the prevalence of nafld in obese or overweight people is higher than general population, and it seems that people with high body mass index (bmi) ...

objective: to determine the prevalence of non-alcoholic fatty liver disease (nafld) in type 2 diabetic patients and to assess its possible risk factors. materials and methods: two hundred and seventy two (186 females and 86 males) diabetic patients were studied. liver ultrasound was performed along with the measurement of such labratoary tests as alanine transaminase, aspartate transaminase, al...

Exposure to polychlorobiphenyls (PCBs) has been reported to affect endocrine glands; however, little is known about the precise toxicological properties of individual PCBs. We determined whether prenatal exposure to 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153), a di-ortho-substituted non-coplanar congener, affects postnatal development in rat offspring. Pregnant Sprague-Dawley rats were given PC...