نتایج جستجو برای: liver protection
تعداد نتایج: 500048 فیلتر نتایج به سال:
BACKGROUND CD4(+) T cell is acknowledged as a key factor in the initiation phase of liver ischemia reperfusion injury. The purpose of current study is to demonstrate the effect of antecedent near-term anti-CD25 monoclonal antibody treatment on IR-induced liver injury by modulation of CD4(+) T cells. METHODS 70% liver warm IR was induced in male C57BL/6 mice after anti-CD25 mAb or non-specific...
When cultured hepatocytes were incubated in cell culture medium at 4 degreesC for up to 30 h and then returned to 37 degreesC, blebbing of the plasma membrane, cell detachment, chromatin condensation and margination, enhanced nuclear stainability with Hoechst 33342, ruffling of the nuclear membrane, and DNA fragmentation occurred. Similar to hepatocytes, cultured liver endothelial cells exhibit...
Background Thyme has high antioxidant properties due to polyphenols and flavonoids. The aim of this study was to evaluate the effects of hepatic protection of Thyme on the toxicity induced by carbon tetrachloride in rats. Materials and methods In this experimental study, 40 male Wistar rats weighing 220-250 grams were randomly divided into five groups of eight. One group was monitored and f...
Alcoholic liver disease (ALD) is the main cause of chronic liver disease across the world and can lead to fibrosis and cirrhosis. The etiopathogenesis of ALD is related to ethanol-induced oxidative stress, glutathione reduction, abnormal methionine metabolism, malnutrition, and production of endotoxins that activate Kupffer cells. Curcumin is an active ingredient of the rhizome of turmeric. The...
The objective of the present study was to investigate the role of nanocarrier of magnetic isotope of 25-Mg2+ (PMC16) in liver toxicity, ATP content and oxidative stress due to malathion (MAL) exposure. PMC16 nanoparticles were administered in different doses (0.05, 0.1 and 0.2 LD50) intravenously (iv) 40 minutes after a single MAL (0.25 LD50= 207 mg/kg) intraperitoneal (ip) injection as a compl...
The tea catechin EGCG has been postulated to provide health benefits in humans, to some extent, as an antioxidant. The dose-response effect of dietary EGCG (0, 30, 60, or 120 mg/kg diet) was tested in rats under high versus low oxidative stress conditions that were created by feeding diets adequate in vitamin E and Se (Lox), or deficient in both (Hox) for six weeks. Effects on growth, quinone r...
introduction: the immunogenicity of crude amoebic antigen and its fractions preparedfrom entamoeba histolytica (nih:200) was evaluated in experimental animals. material and methods: forty two guinea pigs of either sex free from entamoebainfection and aged around 3 to 4 weeks were randomly divided into 5 groups. the treatedgroups consisted of 8, 10, 6, and 8 animals and 10 animals served as cont...
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