conclusions overall, coq10 was determined to have positive effects on liver injury and its related behavioral and biochemical changes. results the serum levels of alanine-aminotransferase (alt), aspartate-aminotransferase (ast), and nh4 show significant increases (p < 0.05). the groups treated with coq10 were shown to have significantly lower clinical grade of encephalopathy (p = 0.001), higher...

Background: Diabetes produces free radicals and damages the liver. The aim of this study was to investigate the effects of Rosmarinus Officinalis leaf hydroalcoholic extract on histopathology and enzymes activity of liver in alloxan induced diabetic rats. Methods: In this study, 50 adult male Wistar rats weighing 200 to 250 grams, were divided randomly into 5 groups of 10; non-diabetic control...

Inflammatory responses in the liver--a central constituent of hepatic wound healing--can be self-limited or persistent depending on the aetiology, liver health state, concentration of toxins or pathogens, and the time frame of exposure to toxins or infection. In case the immune system eradicates a pathogen or in case toxin-exposure is transient, acute hepatitis resolves and the affected liver t...

Objective. To summarize the characteristics and analysis of relevant factors and to give references for prevention and further study of liver damage associated with Polygonum multiflorum Thunb. (HSW), we provide a systematic review of case reports and case series about liver damage associated with HSW. Methods. An extensive search of 6 medical databases was performed up to June 2014. Case repor...

Protecting against liver damage, such as non-alcoholic fatty liver disease, is currently considered to be important for the prevention of adverse conditions, such as cardiovascular and cancerous diseases. Liver damage often occurs in relation to oxidative stress with metabolic disorders, including cellular lipid accumulation. Astaxanthin (3,3'-dihydroxy-β,β-carotene-4,4'dione), a xanthophyll ca...

Nonalcoholic fatty liver disease (NAFLD) is an umbrella term for a range of liver conditions affecting people who drink little to no alcohol. As the name implies, the main characteristic of nonalcoholic fatty liver disease is too much fat stored in liver cells. Nonalcoholic steatohepatitis, a potentially serious form of the disease, is marked by liver inflammation, which may progress to scarrin...

background: activation of inflammatory cells can cause more chemicals induced-hepatotoxicity. aflatoxin b1 (afb1) is a fungal toxin that induces acute hepatotoxicity in humans and animals. this study was conducted to examine the effect of co-exposure lps and various aflatoxin b1 doses on the damage hepatic parameters in isolated perfused rat liver. methods: thirty-two male wistar rats (250-300g...

introduction: liver plays a pivotal role in glucose and lipid homeostasis. this study was undertaken to evaluate the effects of l. acanthodes hydro-alcoholic extract administration on the liver functional and histological parameters in hyperglycemic rats. methods: twenty-four male wistar rats were randomly allocated into four groups control, hyperglycemic (stz), hyperglycemic + insulin (stz+ins...

Liver injury is one of the most common abdominal injuries in patients with severe trauma. A total 2988 concomitant were treated at city clinical hospital named after S.S. Yudin during period from 2010 to 2020, which 371 (12.4%) found have closed Damage liver was revealed 124 (33.4%) The number discharged 78 (62,9%), lethal outcome — 46 (37,1%). severity according ISS (38,1±11,3) points. develop...