INTRODUCTION Alzheimer's disease (AD), the leading cause of dementia, is pathologically characterized by β-amyloid plaques and tau tangles. However, there is also evidence of lipid dyshomeostasis-mediated AD pathology. Given the structural diversity of lipids, mass spectrometry is a useful tool for studying lipid changes in AD. Although there have been a few studies investigating lipid changes ...

pythium irregulare oomycetes adapts with environmental changes including crude oil concentration by changing the composition of lipids in the cytoplasmic membrane and providing the required characteristics for adaptation in improper and stressful environmental situations. it was found that cultivation of pythium irregulare lx oomycetes in the nutrient media with different concentrations of crud...

Longitudinal change in five cognitive abilities was investigated to determine if the direction or magnitude of change was related to the individual's ability level. Adults between 18 and 97 years of age performed three versions of 16 cognitive tests on two occasions separated by an average of 2.7 years. In order to control for influences associated with regression toward the mean, level of abil...

Assessing cognitive change in older adults is a common use of neuropsychological services, and neuropsychologists have utilized several strategies to determine if a change is "real," "reliable," and "meaningful." Although standardized regression-based (SRB) prediction formulas may be useful in determining change, SRBs have not been widely applied to older adults. The current study sought to dev...

It is widely recognized that experience with cognitive tests can influence estimates of cognitive change. Prior research has estimated experience effects at the level of groups by comparing the performance of a group of participants tested for the second time with the performance of a different group of participants at the same age tested for the first time. This twice-minus-once-tested method ...

Does personality change across the entire life course, and are those changes due to intrinsic maturation or major life experiences? This longitudinal study investigated changes in the mean levels and rank order of the Big Five personality traits in a heterogeneous sample of 14,718 Germans across all of adulthood. Latent change and latent moderated regression models provided 4 main findings: Fir...

background: during the procedure of kermanshahi oil production, some changes occur, which might affect the lipid profile of oil. the aim of this study was to investigate the effect of kermanshahi animal oil on the lipid profile in healthy men. methods: twenty five healthy men participated in this clinical trial study. after ten days, wash out period that subjects did not consume kermanshahi ani...

Simultaneous comparisons were made between a freezing-tolerant, cold-acclimating (CA) wild potato species (Solanum commersonii) and a freezing-sensitive, nonacclimating (NA) cultivated species (Solanum tuberosum). Comparative studies allowed differentiation of plasma membrane lipid changes associated with increased freezing tolerance following CA from lipid changes that can result from metaboli...

Animals with anterior or posterior neocortical lesions as well as intact control animals were evaluated for changes in a-adrenergic sensitivity at five postoperative times. Colonic temperature decreases were measured in response to clonidine at each of the postoperative periods. The result indicated that a heightened heat-loss response was induced by clonidine that lasted 21 or more days after ...