We report fatty acid composition in perirenal and buttock adipose tissue in 714 deceased black and white men aged 25-44 yr in New Orleans. Percent saturated fatty acids were higher (p less than 0.001) whereas percent monounsaturated fatty acids were lower (p less than 0.001) in perirenal than in buttock fat. Percent linoleic acid was similar in both races. We conclude that dietary intake of lin...

An endogenous inhibitor of the in vitro binding of the phytotropin N-1-naphthylphthalamic acid to microsomal membranes was detected in extracts prepared from etiolated pea (Pisum sativum L.) epicotyls. Following extensive purification, the inhibitor was identified as linoleic acid. Authentic linoleic acid inhibited N-1-naphthylphthalamic acid binding noncompetitively in a dose-dependent manner,...

Japanese horse chestnut (Aesculus turbinata) seed extract inhibits the activity of cyclooxygenase (COX), but its active constituents have not been identified. In the present study, COX inhibitors were isolated from the hexane extract of this seed by means of 4 steps of liquid chromatography and were identified by gas chromatography/mass spectrometry and nuclear magnetic resonance. The COX inhib...

The absorption of [14C]linoleic acid and [14C]stearic acid in guinea pig bile by the in situ guinea pig gallbladder was compared. Linoleic acid was adsorbed at a faster rate than was stearic acid. Differences were also observed in the incorporation of these two fatty acids into complex lipids of the gallbladder mucosa. A greater portion of adsorbed linoleic acid was incorporated into triacylgly...

The effects of monosomy of specific chromosomes on the fatty acid composition of maize embryos were studied. A novel technique was developed to obtain fatty acid profiles of single embryos without reducing the viability of the sampled kernels. Monosomic 2 embryos had significantly more oleic acid and significantly less linoleic acid than diploid control embryos. Since the conversion of oleic ac...

The essentiality of the n-6 fatty acid, linoleic acid, was established about 80 years ago; the essentiality of the n-3 analogue, a-linolenic acid, became accepted rather later. The intakes of these fatty acids necessary to avoid deficiency are quite low (estimated to be 1 and 0·2 % of energy intake, respectively, corresponding to intakes in adults of about 2 and 0·4 g/d), and all diets should o...

Molecular Interaction of antibiotic Doxycycline hyclate with unsaturated fatty acid, the linoleic acid have been investigated using dilute solution viscosity and ultrasonic techniques at ambient temperature 303 and the physiological temperatures 310 and 313K in the presence of solvent ethyl methyl ketone. The temperatures 310 and 313K are favouring interaction between Doxycycline Hyclate and li...

Cystic fibrosis (CF) is associated with fatty acid alterations characterized by low linoleic and docosahexaenoic acid. It is not clear whether these fatty acid alterations are directly linked to cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction or result from nutrient malabsorption. We hypothesized that if fatty acid alterations are a result of CFTR dysfunction, those alter...