toll-like receptor 4 (tlr4), considered one of  the most important tlr, recognizes lipopolysaccharide of  gram-negative bacteria. recognition  of  ligands by  tlrs  induces signaling pathways resulting in activation of transcriptional factors such as nf-κb which are involved in  the  expression of  inflammatory cytokines and  chemokines. to  prevent  an inappropriate immune response, a complex ...

the innate immune system recognizes the presence of bacterial products through the expression of a family of membrane receptors known as toll-like receptors (tlrs). polymorphisms in tlrs have been shown to be associated with increased susceptibility to diseases such as inflammatory bowel disease. the aim of this study was to determine whether there was a correlation between polymorphisms of tlr...

background and aims: virus-like particles (vlps) have been suggested to be a promising recombinant vaccine approach. several studies have reported that the influenza vlps produced in insect cells is an effective vaccine candidate. due to crucial role of matrix m1 protein in assembly and budding of influenza particles, in all vlps structures, m1 protein have been considered as a main component. ...

several sources were introduced for cell therapy after neurotrauma. there are some evidences that quiescent stem cells are located in the various regions of the adult mammalian brain including cortex, hippocampus, amygdala and striatum. but more study is needed to identify the characteristics of these cells. in the present study we investigated the possibility of isolating neural stem cells fro...

conclusions candida strains isolated from newborns, elderly patients, and intensive care patients, identified and isolates from blood cultures, should be studied for antifungal susceptibility for management of the treatment. our university hospital is a recently opened center and these are the first data of our center. gradually, as the number of patients increases, this data will be evaluated ...

b-carboline alkaloids such as harmaline and nicotine are naturally present in the human food chain. plants which contain b-caroline have anxiety and hallucinogenic effects. in this study the change in like – anxiety behaviors was investigated after intra- amygdala injections of nicotine and harmaline and intra action of them in male rat. different doses of harmaline, nicotine and its compounds ...

kruppel-like factors (klfs) are a highly related zinc-finger family of transcription factors implicated inthe regulation of the eukaryotic cellular growth and differentiation of a diverse set of cells in mammal. usingrt-pcr technique, a 456 bp cdna fragment encoding n-terminus part of a klf2b was isolated from the skinmucosa of common carp (cyprinus carpio) using two degenerative oligonucleotid...