OBJECTIVE Avoiding potentially irritating contact is a key point in vulvar lichen simplex chronicus (VLSC) management. This study aims to assess the use of nonirritating silk fabric underwear (Dermasilk) as an adjuvant tool in the treatment of VLSC. METHODS Twenty women with VLSC were enrolled in a 1-week open-label active treatment phase with topical 0.1% mometasone furoate (MMF) ointment. P...

This 48-year-old man first presented to a referring hospital in 1998 with non-specific nephrosclerosis on renal biopsy and focal scars on [99]Tc[m]-dimercaptosuccinic acid scans. His serum creatinine was 279 mmol/l. His care was transferred to the Royal London Hospital in February 2004 at which time his serum creatinine was 868 mmol/l (estimated glomerular filtration rate of 6ml/min/1.73m), wit...

BACKGROUND An association between lichen simplex chronicus (LSC) and sexual dysfunction was explored. However, no data are available from investigations into the relationship between erectile dysfunction (ED) and LSC. OBJECTIVES This retrospective population-based cohort study aimed to clarify the risk of ED associated with LSC. METHODS By using the Taiwan National Health Insurance Research...

Background: Pain and pruritus are two common symptoms in dermatology that are transmitted with unmyelinated C fibers via substance P. Topical capsaicin is effective due to depletion of never endings from substance P. Objective: The efficacy and side effects capsaicin gel in painful and pruritic skin disorders was compared to placebo. Patients and Methods: In a controlled clinical trial, 4...

Background: Pruritic skin disorders are one of the most common disorders in elderly. Objective: To find out the prevalence of pruritic skin disorders in the elderly residing in Kahrizak Institute in Tehran. Patients and Methods: In this descriptive, cross sectional survey, all the elderly over 60 years of age without dementia residing in Kahrizak Institute in Tehran in the first 6 months ...