Purified CF1 (chloroplast coupling factor 1) synthesizes enzyme-bound ATP (CFltATP) from medium Pi. The reaction does not depend on medium ADP, indicating that the ADP substrate is tightly bound to CF1 (CFltADP). At saturating pi] and at the pH optimum of 6.0, a yield of 0.25 mol of ATP/mol of CF1 was obtained. The addition of hexokinase and glucose does not reduce the yield of CFl<ATP, showing...

Always use the definitive version when citing. Number of characters in the title: 85 Running title: Mitochondria and Lewy body formation. ubiquitin proteasome system. Abstract Objective: Alpha-synuclein protein aggregates and mitochondrial dysfunction have both been described in substantia nigra neurons from patients with idiopathic Parkinson's disease and dementia with Lewy bodies. We explored...

In implicit upwind methods for the solution of linearized Euler equations, one of the key issues is to balance large time steps, leading to a fast convergence behavior, and small time steps, needed to sufficiently resolve relevant flow features. A time step is determined by choosing a CourantFriedrichs-Levy (CFL) number in every iteration. A novel CFL evolution strategy is introduced and compar...

BACKGROUND Magnetic resonance (MR) techniques used to detect lesions of the ligament complex for articulation of the ankle lack the desired accuracy for the study of the calcaneofibular ligament (CFL). The lack of sensitivity of the conventional techniques is due to variations in the dimensions of the CFL. The best results are obtained when the image plane is oriented parallel to the ligament. ...

In neutral cold quark matter that is sufficiently dense that the strange quark mass Ms is unimportant, all nine quarks (three colors; three flavors) pair in a color-flavor locked (CFL) pattern, and all fermionic quasiparticles have a gap. We recently argued that the next phase down in density (as a function of decreasing quark chemical potential μ or increasing strange quark mass Ms) is the new...

This study examined how the uneven influx of red blood cells (RBCs) from feeding vessels influences formation of cell-free layer (CFL) in the downstream vessel of a venular bifurcation. Spatio-temporal variations of the CFL width along the downstream vessel (19-41-μm inner diameter, D) were determined at 0.5D intervals from 0.5D to 3.0D away from the bifurcation. Upstream flow conditions were q...

We calculate neutrino emissivities from the decay and scattering of Goldstone bosons in the color-flavor-locked (CFL) phase of quarks at high baryon density. Interactions in the CFL phase are described by an effective low-energy theory. For temperatures in the tens of keV range, relevant to the long-term cooling of neutron stars, the emissivities involving Goldstone bosons dominate over those i...

Coronafacic acid (CFA), the polyketide component of the phytotoxin coronatine (COR), is activated and coupled to coronamic acid via amide bond formation, a biosynthetic step presumably catalyzed by the CFA ligase (cfl) gene product. The COR biosynthetic gene cluster in Pseudomonas syringae pv. glycinea PG4180 is located within a 32-kb region of a 90-kb plasmid designated p4180A. In the present ...

The frequency of droughts and floods is increasing due to the extreme climate. Therefore, water resource planning, allocation, disaster prevention have become increasingly important. One most important kinds hydrological data in resources planning management discharge. general way measure depth discharge use Acoustic Doppler Current Profiler (ADCP), a semi-intrusive instrument. This method woul...

The authors assessed the accuracy of published clinical criteria and their own modifications of those criteria in diagnosing Lewy body disease (LBD). Clinical diagnoses were made by two clinicians, blinded to neuropathologic diagnoses, using the Rochester Alzheimer's Disease Center database and traditional medical records. Neuropathologic diagnoses were made according to published guidelines. R...