Leprosy, a disease caused by Mycobacterium leprae, primarily affects the skin and nerves, but the nails are also involved in as many as 3 out of 4 patients .The factors that trigger nail changes in leprosy are numerous and include repeated trauma, neuropathy, vascular impairment, infections, lepra reactions, and the drugs used to manage the disease. The changes most often reported include subun...

Occurrence of squamous cell carcinoma (SCC) in the nail is rare [1], although it is the most common epithelial malignancy of the nail apparatus [1, 2]. Less than 300 cases of subungual SCC (invasive or in situ) have been reported in the English-language literature [2]. The clinical diagnosis of this type of tumor may be difficult and is often missed and/or delayed because of the heterogeneity o...

A double-blind, randomized, vehicle-controlled, parallel-group trial was performed to compare the efficacy and tolerability of tazarotene 0.1% gel and vehicle gel in 31 patients with fingernail psoriasis. Patients were randomized to receive tazarotene or vehicle gel, which they applied each evening for up to 24 weeks to 2 target fingernails, one under occlusion and one unoccluded. The tazaroten...

UNLABELLED Introduction. Patients with chronic kidney disease on hemodialysis (HD) undergo many dermatological signs and symptoms during treatment. The aim of this study was to investigate the prevalence of skin manifestations among the patients on maintenance HD in the HD center of Boo Ali-Sina Hospital (Qazvin, Iran) and compare them with the general population. METHODS From June 2012...

In the ripe eggs of all species of marine teleost fish so far examined, retinal (vitamin A aldehyde) is the predominant form of vitamin A, and in some species it represents 90% of the total vitamin A-active material in the eggs (Plack, Kon & Thompson, 1959; Plack & Kon, 1961). Hen’s eggs also contain retinal and, for forty-one eggs from six hens on a diet of breeder’s mash, a value of 21.7 pg/e...

Psoriasis is a common skin disease, with nail involvement in approximately 80% of patients. Nail psoriasis is often associated with psoriatic arthropathy. Involvement of the nails does not always have relationship with the type, gravity, extension, or duration of skin psoriasis. Nail psoriasis can occur at any age and all parts of the nails and the surrounding structures can be affected. Two cl...