Sub-lethal studies of chlorpyrifos, O,O-diethyl-O-(3,5,6-trichloro-2-pyridyl) phosphorothioate on mosquito fish, Gambusia affinis were carried out in vivo, for 20 days to assess the locomotor behavior in relation to bioaccumulation and interaction with a targeted enzyme, acetylcholinesterase (AChE, EC: 3.1.1.7). Fish exposed to sub-lethal concentration of 60 microg/L (1/5 of LC 50) were under s...

7-con-O-Methylnogarol (7-OMEN) is a new anthracycline antitumor agent with significant activity in vivo against murine P388 and L1210 leukemia (140% increase in life span) and B16 melanoma (114% increase in life span). We report here the complex relationship that exists between intracellular drug concentration and killing of Chinese hamster ovary (CHO), B16, and L1210 cells in culture by 7-OMEN...

The aim of this study was to investigate the lethal and sublethal toxicity of a methomyl-based insecticide in Hoplobatrachus rugulosus, as methomyl-based insecticides are applied in massive amounts and agrochemicals have effects on the decline in amphibian populations. To evaluate the toxic effects of methomyl from agricultural application, a methomyl-based insecticide containing 40% methomyl w...

Water temperature is an abiotic master variable for the survival of aquatic organisms. Global warming alters thermal regimes rivers and, thus, poses a threat to freshwater biodiversity. To address impacts water changes related global on fish species in life cycle assessment (LCA), we developed spatially explicit characterization factors (CFs) 207 greenhouse gases under four representative conce...

Abstract Oleander ( Nerium oleander L.) is a shrubbery plant with various functions as an ornamental, medicinal, bio-fungicide, and bio-insecticide. The study aimed to investigate the acute toxicity assay of methanolic extract leaves on fall armyworm Spodoptera frugiperda J.E. Smith). was conducted in Complete Randomized Design (CRD) for upper lower concentrations. concentrations’ results were ...

The petroleum ether and chloroform fractions of ethanol extract of leaf and stem from the plant Passiflora edulis (Fam: Passifloraceae) was subjected to antioxidant, antibacterial and cytotoxic activity. All the fractions showed potent antioxidant activity, of which the chloroform and petroleum ether fraction of stem demonstrated the strongest antioxidant activity with the IC50 value of 51.28 μ...

THE MINIMAL LETHAL CONCENTRATION OF OZONE IN WATER WAS DETERMINED FOR THREE BACTERIAL SPECIES: Escherichia coli, Bacillus cereus, and Bacillus megaterium. A contact period of 5 min was selected. The lethal threshold concentration for the cells of B. cereus was 0.12 mg/liter while that for E. coli and B. megaterium was 0.19 mg/liter. Low concentrations of ozone were ineffective when organic matt...

Here, we report the results of a study on the effects of ethanol exposure on human red blood cells (RBCs) using quantitative phase imaging techniques at the level of individual cells. Three-dimensional refractive index tomograms and dynamic membrane fluctuations of RBCs were measured using common-path diffraction optical tomography, from which morphological (volume, surface area, and sphericity...

In vitro efficacy of methanolic extract of Atropa belladonna and its components scopolamine and atropine was assessed against Rhipicephalus (Boophilus) microplus. Five concentrations of the extract (1.25%, 2.5%, 5%, 10%, and 20%) were used whereas scopolamine and atropine were each tested at 0.1%. In adult immersion test, the extract was lethal to ticks at 20% concentration. The LC50 and LC95 v...