Leprosy is a chronic and systemic infection caused by Mycobacterium leprae. According to the World Health Organization, the prevalence of leprosy registered at the beginning of 2008 stood at 212,802 cases. Thanks to anti-leprosy multidrug therapy the number of new cases detected globally has fallen. Lagophthalmos can appear in newly diagnosed lepromatous patients and in patients under anti-lepr...

Leprosy control programs, including multi-drug therapy for leprosy, have undergone significant changes over the last few years. With the process of integration of leprosy into general health services taking place all over India, dermatologists are more responsible for the care of leprosy patients than ever before. This article attempts to highlight some of the important changes in control progr...

Leprosy is a chronic and debilitating human disease caused by infection with the Mycobacterium leprae bacillus. Despite the marked reduction in the number of registered worldwide leprosy cases as a result of the widespread use of multidrug therapy, the number of new cases detected each year remains relatively stable. This indicates that M. leprae is still being transmitted and that, without ear...

INTRODUCTION Leprosy is a chronic infection caused by Mycobacterium leprae. Selenium, on the other hand, is a substance, which is needed for its protective role against microorganism infection. AIM This study aims to know the association between selenium serum levels with bacteriological index. METHODS This is an analytical cross-sectional study model. Sampling was done with consecutive sam...

After successful control of the endemic of leprosy in Shandong Province, China, how to deal with ex-leprosy patients living in the leprosy villages/leprosaria has become a hot topic among programme managers, medical staff and governmental officials at different levels. One of the possible solutions in dealing with the problem was proposed to combine small leprosy villages into a few larger, alr...

Leprosy is a chronic infectious and neurological disease caused by Mycobacterium leprae, an unculturable pathogen with massive genomic decay and dependence on host metabolism. We hypothesized that mitochondrial genes PARL and PINK1 would confer risk to leprosy. Thirteen tag SNPs of PARL and PINK1 were analyzed in 3620 individuals with or without leprosy from China. We also sequenced the entire ...

To assess the successes of the leprosy elimination strategy before (2000 to 2005) and after (2006 to 2010) eradication period in referral hospital of Tamilnadu District. Retrospective cross-sectional study of all registered new cases of leprosy carried out from records over a ten year period from referral Sacred heart leprosy hospital, Kummbakkonam, Tamil Nadu. During the survey, total number o...

The objective of this study was to find a specific B-cell epitope of N-terminal region of antigen L-ESAT-6 from leprosy patients, healthy individuals and healthy nurses working for more than 10 years in the leprosy ward of Dr. A. Rivai Abdullah Leprosy Hospital, Palembang, Indonesia. Fifty subjects were enrolled in this study, comprising 10 subjects with LL type leprosy, 10 subjects with BB typ...

Background. Leprosy is a chronic infectious disease that presents with varying dermatological and neurological symptoms. The leprosy reactions occur over the chronic course of the disease and lead to extensive disability and morbidity. Objective. To analyze and identify the risk factors which contribute to leprosy reactions. Methods. In a retrospective study, we reviewed the medical records of ...

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae) that involves the integumentary and peripheral nervous system, causing neuropathy, deformity, disability. Early detection appropriate treatment are ways to break chain of transmission prevent disability in leprosy patients. The first line for standard Multidrug Therapy (MDT) regiment consisting rifampicin, dapson...