Acetaminophen (N-acetyl-p-aminophenol, APAP) is the most popular drug recommended and consumed for relieving mild moderate pain fever. Although effective in therapeutic doses, APAP overdose induces hepatotoxicity, causing acute liver failure. In this study, hepatoprotective effects underlying mechanisms of Lavandula officinalis essential oil (LEO) were investigated APAP-induced hepatotoxicity. ...

The use of essential oils (EOs) and their components is known since long in traditional medicine and aromatherapy for the management of various diseases, and is further increased in the recent times. The neuroprotective and anti-aging potentials of EOs and their possible mechanism of actions were evaluated by numerous researchers around the globe. Several clinically important EOs and their comp...

The xeromorphic adaptation of epidermal cells of Lamiaceae plant leaves, the conse­ quence of their adaptation to an arid habitat, was investigated. These xerophytic species inhibit transpiration in different ways, depending on the number, the form and the position of trichomes, whether they are dead hairs or live glandular structures. The Salvia genus is characterized on one hand by multicellu...

In this study, 17 edible flowers (Allium ursinum L., Borago officinalis Calendula Centaurea cyanus Cichorium intybus Dianthus carthusianorum Lavandula angustifolia Mill., Leucanthemum vulgare (Vaill.) Lam., Paeonia Primula veris Robinia pseudoacacia Rosa canina pendulina Salvia pratensis Sambucus nigra Taraxacum officinale Weber, and Tropaeolum majus L.) were investigated to assess their sensor...

Essential oil components were extracted from Lavandula angustifolia (Lavender) flowers using pressurized fluid extraction (PFE). A Box-Behnken design was used to optimize the effective extraction variables. The chemical composition of extracted samples was analyzed by gas chromatograph-flame ionization detector column. For achieving maximum % extraction yield the temperature, pressure, and dyna...

The antioxidant activity of five samples of Lavandulae flowers (L. angustifolia ssp. angustifolia, L. hybrida, L. angustifolia spp. pyrenaica, L. angustifolia spp. angustifolia cv. Munstead and cv. Hidicote Blue) harvested from Romania was investigated using DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging and ferrous ion chelating assays. Total polyphenolic content (mg/g dried extract) ...