background beta-lactam resistance in gram-negative bacteria, especially escherichia coli, is a main clinical problem. it is often caused by the co-production of β-lactamases, particularly extended-spectrum β-lactamases (esbls) and ampc enzymes. it may lead to a problem for diagnosis via recommended phenotypic tests by the clinical and laboratory standards institute (clsi). conversely, β-lactama...

background and objectives: pseudomonas aeruginosa is a frequent opportunistic pathogen in health care associated infections that is highly resistant to the majority of β-lactams. the aims of this study were to access the antimicrobial susceptibility pattern of p. aeruginosa isolated from educational hospitals of qazvin and alborz provinces, to determine the prevalence of metallo-β-lactamase (mb...

The dissemination of plasmid-mediated antimicrobial resistance genes may pose a substantial public health risk. In the present work, the occurrences of blaCTX-M and plasmid-mediated ampC and qnr genes were investigated in Escherichia coli from 16 chicken carcasses produced by four commercial brands in Brazil. Of the brands tested, three were exporters, including one of organic chicken. Our stud...

Background and Aim: Escherichia coli causes a bacterial illness that frequently affects cats. Diseases caused by E. are treated using antibiotics. Because of their proximity to humans, cats possess an extremely high risk contracting antibiotic resistance genes when owners touch cat feces containing harbor genes. This study was conducted identify multidrug-resistant extended-spectrum β-lactamase...

conclusions regarding the importance of metallo-beta-lactamase (mbl) produced by pseudomonas spp. isolated from hospitals, quick identification of clinical samples should be considered as an important and basic step to treat and control infections caused by pseudomonas spp. results strains with mic > 4 µg/ml were investigated by phenotypic and genotypic methods. in the current study the rate of...

Background & Objective: The production of plasmid-mediated AmpC beta-lactamases (PMABLs) among urinary Klebsiella pneumoniae isolates causes a severe problem to the successful treatment of urinary tract infections (UTIs). This study was designed to evaluate antimicrobial resistance, the presence of AmpC beta-lactamase genes, and the genetic relatedness among K. pneumoniae strains separated from...

We report the selection in a 15-year-old boy of a multidrug-resistant, extended-spectrum β-lactamase (ESBL)-producing Aeromonas salmonicida after medicinal leech therapy that required an antibiotic prophylaxis based on piperacillin/tazobactam and cotrimoxazole. Whole genome sequencing of the strain indeed revealed 13 antibiotic resistance genes, including the ESBL CTX-M-3 and the unusual β-lact...

Antimicrobial susceptibility testing of clinical isolates is a crucial step toward appropriate treatment of infectious diseases. The clinical isolate Francisella philomiragia 14IUHPL001, recently isolated from a 63-year-old woman with atypical pneumonia, featured decreased susceptibility to β-lactam antibiotics when cultivated in 5% CO2. Quantitative β-lactamase assays demonstrated a significan...

Pseudomonas aeruginosa (P. aeruginosa) places among major opportunistic nosocomial pathogen which has developed extensive drug resistance. Due to uncontrolled consumption of antibiotics, multidrug-resistant (MDR) P. species are increasingly isolated from various settings hospitals globally. This research aimed determine the genes reproducing blaOXA-48, blaIMP-1, blaVIM-1 and blaNDM-1 metallo be...