نتایج جستجو برای: laboratory animal
تعداد نتایج: 475740 فیلتر نتایج به سال:
A new law controlling the use of animals in scientific experiments is likely to come into force in Britain this year. A government bill called Animals (Scientiflc Procedures) is now passing through parliament. New legislation is long overdue. Biology has undergone a revolution since 1876 when Britain last enacted a major piece of legislation. Scientific knowledge of what is and what is not like...
The 3Rs principle of replacement, reduction, and refinement has increasingly been endorsed by legislators and regulatory bodies as the best approach to tackle the ethical dilemma presented by animal experimentation in which the potential benefits for humans stand against the costs borne by the animals. Even when animal use is tightly regulated and supervised, the individual researcher's respons...
The use of animals in experimental research parallels the development of medicine, which had its roots in ancient Greece. The increasing demand for high-standard animal models, together with a critical view of the way animals are used, has led to the development of a multidisciplinary branch of science we now know as 'laboratory animal science'. The guiding principles are replacement, reduction...
Improving laboratory animal science and welfare requires both new scientific research and insights from research in the humanities and social sciences. Whilst scientific research provides evidence to replace, reduce and refine procedures involving laboratory animals (the '3Rs'), work in the humanities and social sciences can help understand the social, economic and cultural processes that enhan...
CONTEXT Publication bias jeopardizes evidence-based medicine, mainly through biased literature syntheses. Publication bias may also affect laboratory animal research, but evidence is scarce. OBJECTIVES To assess the opinion of laboratory animal researchers on the magnitude, drivers, consequences and potential solutions for publication bias. And to explore the impact of size of the animals use...
An institutional training program for animal care and veterinary technicians should be planned and implemented to provide these individuals with knowledge and skills for performing their duties within a laboratory animal care and use program. The complexity in the regulatory and scientific features of the animal research environment necessitates a strong training program on diverse topics accor...
Institutional Animal Care and Use Committees (IACUCs) were created to review, approve and oversee animal experiments and to balance the interests of researchers, animals, institutions and the general public. This study analyzed the overall membership of IACUCs at leading U.S. research institutions. We found that these committees and their leadership are comprised of a preponderance of animal re...
The Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA) in India is one of a kind in the world. It is a statutory body of the government of India formed by an act of the Indian parliament. This body consists of nominated members and representatives from national regulatory agencies, Ministry of Health and Family Welfare, Ministry of Environment and Forests, n...
Background: Advancements made in medicine during centuries have been disclosed importance of using animal for research in biology. Appropriate conduction of animal researches needs skilled and experienced researchers who are aware of principles for using laboratory animals. Regarding scientific activities, ethical considerations for using of animals in experiments that are associated with pain ...
Practical implementation of the 3Rs at national and regional levels around the world requires long-term commitment, backing, and coordinated efforts by international associations for laboratory animal medicine and science, including the International Association of Colleges of Laboratory Animal Medicine (IACLAM) and the International Council for Laboratory Animal Science (ICLAS). Together these...
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