The efficacy of labetalol, an alpha and beta receptor antagonist, was evaluated in 12 normotensive patients with stable angina pectoris in a single blind dose ranging study. After a two week period of placebo treatment, labetalol was given in doses of 100, 150, 200, and 300 mg twice daily, each for two weeks. Frequency of angina attacks decreased from 9.4 (SEM 2.3)/week in the control period to...

BACKGROUND Rhinoplasty is one of the most common surgeries of the plastic surgery and as well as ear, throat and nose. Intra-operative bleeding during surgery is one of the most important factors that may impair the surgeon's job. Providing a clean blood-free surgical filed makes the operation faster, easier and with a better quality. One way to achieve this goal is to induce hypotension. This ...

ambulatory blood pressure (BP) as well as on the magnitude of leg edema of treatments using LER, amlodipine (AML), or hydrochlorothiazide (HCT) in patients with confirmed ambulatory hypertension (daytime systolic BP 135mmHg). A total of 121 eligible patients (66M/55F, mean age of 62.7 7.1 yrs) were randomized to either LER 10 mg (n 39), AML 5 mg (n 39) or HCT 12.5 mg (n 43) for 4 weeks. They we...

Objective: To evaluate the glutathione (GSH), lipid peroxidation, total antioxidant status levels (TAS), and liver function parameters such as serum aspartate transaminase (AST) and serum alanine transaminase (ALT) in South Indian hypertensive patients before and after olmesartan and labetalol treatment. Methods: Total 69 subjects were selected for the study. Out of 69 subjects, 29 were healthy...