[Chemical reaction: See text] The synthesis of a series of stevastelin analogues with modification of the susbstituent at the C-2 position of the stearic acid chain (compounds 28 and 31), variation of the amino acids (compounds 41, 42, 73, and 78), or lacking the lipidic chain (compound 91) is described. The replacement of L-valine and L-threonine with other amino acids proceeded without diffic...

As a follow-up to our effort establish reliable thermodynamic data for amino acids, the heat capacity and phase behavior are reported N-acetyl glycine amide (CAS RN: 2620-63-5), N-acetyl-L-alanine 15962-47-7), N-acetyl-L-valine 37933-88-3), N-acetyl-L-isoleucine 56711-06-9), N-acetyl-L-leucine 28529-34-2). Prior measurement, thermogravimetric analysis X-ray powder diffraction were performed det...

In this work results of neutron powder diffraction and inelastic neutron scattering on ali‐ phatic amino acid (L-alanine, L-valine and L-leucine) crystals are presented. The study al‐ lows inferring important informations about both the stability of the structures and the dynamics of phase transitions. In particular, it was possible to compare the behavior of different amino acids and to infer ...

The presence of two kinds of l-amino acid dehydrogenase in resting spores of Bacillus subtilis was indicated. One of them was l-alanine dehydrogenase, which used only l-alanine as a substrate, and the other was nonspecific dehydrogenase, which used l-valine, l-isoleucine, l-leucine, and l-alanine (slightly) as substrates. Several properties of these dehydrogenases were compared.

The conversion of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to isopenicillin N is dependant on the catalytic action of isopenicillin N-synthase (IPNS), an important enzyme in the penicillin and cephalosporin biosynthetic pathway. One of the amino acid residues suggested by the Aspergillus nidulans IPNS crystal structure for interaction with the valine isopropyl group of ACV is prol...

1. The intracellular concentrations of sodium, potassium, ATP and creatine phosphate in chopped tissue from guinea-pig cerebral cortex were altered by a 10min period of electrical stimulation. 2. The ability of the tissue to take up l-[(14)C]valine and incorporate it into protein was tested at various times after the cessation of electrical stimulation. 3. The restoration of the ability of the ...

The conductivity and spectrophotometry techniques were employed to evaluate the binary ternary complexes of divalent metal ions Co(II) Cu(II) with physiologically relevant amino acid L-Valine (Val) analgesic paracetamol. experiments generated by direct equation from titration data, while performed using continuous variations approach (Job's method). Both accomplished in an aqueous solution a co...

Incorporation of selected amino acids by resting cells was studied with regard to effects of concentration, rate and extent of incorporation, cellular distribution, effect of ammonium ion on uptake, and competitive effects. l-Aspartic acid, l-alanine, l-serine, and glycine presented at trace levels were incorporated at rates ranging from 0.11 to 8.2 mumumoles per mg (dry weight) per minute, and...