Objective(s): To design a multivalent DNA vaccine encoding the most immunogenic regions of the Leishmania major antigens including TSA (Thiol-specific antioxidant protein), LmSTI1 (Leishmania major stress-inducible protein1), LACK (Leishmania homologue of receptors for activated C Kinase), and KMP11 (kinetoplastid membrane protein-11) on BALB/c mice.M...

Legumes are of great economic importance. Depending on the species, they cultivated for food, fodder, green manure, and even as ornamentals. Legume seeds contain many valuable nutrients also anti-nutritional substances. The aim study is to compare important seed quality traits in pea (Pisum sativum L.), faba bean (Vicia white lupin (Lupinus albus narrow-leafed angustifolius yellow lupine luteus...

The study was conducted to determine the plasma concentrations and pharmacokinetic parameters of rafoxanide after a single intravenous (10 mg/kg) and oral (22.5 mg/kg) administrations in black Bengal female goats. Maximum (87.63 11.71 mg/mL) and minimum (1.8 0.24 mg/mL) plasma concentrations of rafoxanide were recorded at 0.08 and 12 h respectively after i.v. administration. The elimination h...

Background: CE is a zoonotic parasitic infection caused by Echinococcus granulosus worldwide and is associated with economic losses among livestock animals. EG95 is an immunogenic antigen from the E. granulosus. Lactococcus lactis has been prested as a safe vehicle for antigen delivery. The goal of this study was to design a novel L. lactis strain displaying EG95 as a vaccine delivery system. M...

background: surveillance of the canine reservoir is highly important to help control of visceral leishmaniasis in human. it is therefore imperative to improve and develop new tools reliable, easy to use, and cheap for the diagnosis of canine leishmani asis. k39 sub recombinant antigen of leishmania infantum was expressed in prokaryotic system and evaluated for sero-diagnosis of canine visceral ...

This study comprised 136 meat samples (m. longissimus lumborum) from pork carcasses of six-month-old crossbred porkers derived ♀ (Polish Large White×Polish Landrace)×♂ (Duroc×Pietrain), with an average carcass weight 85.8 ± 8.5 kg, slaughtered on industrial processing line. The pH1, pH24, pH48, WHC, colour parameters (L*, a*, b*), moisture content, crude protein, intramuscular fat, and water-so...

Background: Hepatitis delta virus (HDV) is a subviral human pathogen that exploits host RNA editing activity to produce two essential forms of the sole viral protein, hepatitis delta antigen (HDAg). Editing at the amber/W site of HDV antigenomic RNA leads to the production of the large form (L-HDAg), which is required for RNA packaging. Methods: In this study, PCR-based site-directed mutagen...