Acute pancreatitis (AP) is a life-unpleasant situation with contradictory and inadequate treatments. In this regard, the present study evaluated effect of possible pretreatment lipase-pancreatin on L-arginine-induced AP. Forty adult mice were selected divided into five groups: I) control group, II III) AP groups (i.p.) receiving L-arginine 2×300 2×400 mg/100 g body weight (b.w.), IV) (2×300 L-a...

Objective(s): Growing evidence demonstrates that L-arginine/NO/cGMP/KATP channel pathway has a modulatory role in pain perception. Previous studies have shown that thymoquinone exerts antinociceptive effects; however, the mechanisms underlying antinociception induced by thymoquinone have not been fully clarified. The aim of the present study was to evaluate the role of L-arginine/NO/cGMP/KATP c...

introduction: prenatal stress has deleterious effects on the development of the brain and is associated with behavioral and psychosocial problems in childhood and adulthood. this study aimed to determine the protective effect of l-arginine on fetal brain under maternal stress. methods: twenty pregnant wistar rats (weighting 200-230 g) were randomly divided into 4 groups (n=5 for each group). th...

Introduction L-Arginine is a semi-essential amino acid involved in numerous areas of human physiology, including production of nitric oxide (NO) – a key messenger molecule involved in vascular regulation, immune activity, and endocrine function. Arginine is also involved in protein production, wound healing, erectile function, and fertility. Arginine is not considered essential because humans c...

The present review will give an overview of the biochemistry and metabolism of L-arginine focusing on the mechanisms which may either provide or limit cellular availability of this amino acid for nitric oxide synthases and arginase / polyamine pathway and describe possible interactions between these pathways. In addition, emerging species differences in the expression and role of arginases are ...

Introduction L-Arginine is a semi-essential amino acid involved in numerous areas of human physiology, including production of nitric oxide (NO) – a key messenger molecule involved in vascular regulation, immune activity, and endocrine function. Arginine is also involved in protein production, wound healing, erectile function, and fertility. Arginine is not considered essential because humans c...

The paper presents comparative data on the effectiveness of complex treatment acute condyloma anogenital region (n = 105). Destruction genital warts was performed surgically, preceded by immunomodulatory and antiviral systemic therapy local with antiseptic measures hyaluronic acid, which continued in postoperative period. Patients first group 70) were added to drug - nitrogen donor L arginine. ...