Early knee osteoarthritis poses a therapeutic dilemma to the musculoskeletal clinician. Despite the recent interest in arthroscopic and injectable regenerative therapies intended to repair or restore a focal target such as cartilage, meniscus, or subchondral bone, none have been shown to slow disease progression. A likely cause of these disappointing treatment outcomes is the failure to address...

Background: Knee osteoarthritis (KOA) causes joint pain and dysfunction that severely affects the patient’s ability to walk. Arthroscopy combined with intraarticular injection of sodium hyaluronate can slow development knee osteoarthritis, but there is a lack rigorous evidence-based medicine evaluation, it has not been recognized by some scholars at home abroad. This paper analyzed clinical eff...

Osteoarthritis is a degenerative joint disease which related with the damage of cartilage. X-Ray one osteoarthritis radiological examinations but only to see bone not One an effective examination visualize cartilage Ultrasound. The objective this study determine relation between grading scale ultrasonographic in knee patients. This was Cross-sectional on 32 patients based Total Sampling techniq...

OBJECTIVE To assess the clinical relevance of mean and minimum femorotibial joint space narrowing (JSN) for predicting future osteoarthritis related surgery in patients with knee osteoarthritis. METHODS 126 subjects with primary knee osteoarthritis were followed prospectively for a mean eight years. Minimum and mean joint space width (JSW) were assessed from standard x rays at baseline and af...

Introduction Osteoarthritis (OA), also known as degenerative joint disease is the most common form of arthritis and a leading cause of disability worldwide. Osteoarthritis of the knee is one of the five leading cause of physical disability in non-institutionalized elderly men and women. OA knee, along with osteoarthritis of the hip affects the ability to walk and climb stairs more than any othe...

BACKGROUND The association between progression of knee osteoarthritis and progression of osteoarthritis at sites distant from the knee is unclear because of a lack of multisite longitudinal progression data. OBJECTIVE To examine the association between radiological progression of knee osteoarthritis and osteoarthritis of the hands, hips, and lumbar spine in a population based cohort. METHOD...

INTRODUCTION Total joint replacement is considered a surrogate measure for symptomatic end-stage osteoarthritis. It is unknown whether the adipose mass and the distribution of adipose mass are associated with the risk of primary knee and hip replacement for osteoarthritis. The aim of the present investigation was to examine this in a cohort study. METHODS A total of 39,023 healthy volunteers ...

Knee osteoarthritis (KOA) is a common degenerative joint disease and immune system dysregulation has been implicated in its pathogenesis. The effect of arthroscopic knee surgery, an important method for KOA diagnosis and treatment, on the expression of immune regulators remains poorly understood. We aimed to investigate the clinical efficacy of such surgery and its impact on IL-1β, CXCL13, and ...

Background: One of the most important issues for patients with osteoarthritis is reducing pain and returning them to normal life. In addition to losing weight and improving daily activities, pain management treatments may be needed. One of these treatments is the injection of hyaluronic acid gel into the knee joint, which has been studied in this study. Methods: In this stud...