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Background: Gensenoside Rh2 is an anticancer drug with low toxicity and stability in the body. The aim of this study was to evaluate the blood toxicity of functionalized graphene-arginine with anticancer drug ginsenoside Rh2 in balb/c mouse model with breast cancer. Materials and Methods: Graphene-Arginine (G-Arg) and Graphene-Arginine-ginsenoside Rh2 (G-Arg-Rh2) were synthesized using microwa...
زمینه و هدف:با توجه به نقش گیرنده های gaba در افسردگی، مطالعات نشان داده اند که گیرنده های gabab در تعدیل مسیرهای سرتونرژیک و آدرنرژیک نقش دارند،از این رو هدف از مطالعه ی حاضر بررسی اثر داروی باکلوفن(آگونیست گیرنده ی gabab) و نقش کانال های پتاسیم در اثر ضد افسردگی داروی باکلوفن در موش سوری می باشد.روش بررسی: در این مطالعه اثر داروی فلوکستین، باکلوفن، گلی بنکلامید و کروماکالیم توسط آزمون شنای اج...
CD4+CD25+FOXP3+ is a regulatory T cell that plays role in the body's tolerant system to control activated effector cells. an important as trigger for tumor progressiveness, where increase amount of FOXP3 state correlates with poor prognosis. Breast cancer type tends every year. The purpose this study was influence combination Phyllanthus urinaria and Catharanthus roseus plant extracts on modula...
Background: The aim of this study was to investigate the possible protective role of melatonin on the apoptosis of germ cells in chemotherapy-induced spermiotoxicity. Materials and Methods: Male adult NMRI mice were divided into four groups. Then each group were divided into two subgroups of a and b. Group 1 (control): mice received vehicle (ethanol 1%) for 5 days; Group2 (Busulfan): mice recei...
This paper discusses the electrochemical energy storage and room temperature hydrogen, methane carbon dioxide adsorption/desorption behaviour of commercial nanoporous activated having a specific BET surface area 1007 m2 g−1 pore volume 0.371 cm3 g−1. The was determined from its capacitive performance using standard three two-electrode cells. capacitance (CS) sample three-electrode cell is 138 F...
The mechanisms by which human oligodendroglial cells, KG-1-C cells, phagocytose mycobacteria, especially Mycobacterium leprae, were studied. The ability of glial cells to phagocytose M. leprae was inhibited by azide, dinitrophenol (inhibitors of oxidative phosphorylation), and iodoacetamide but not fluoride (both are inhibitors of glycolysis). Thus, the energy metabolism dependency is somewhat ...
In vitro antioxidant and erythrocyte protecting activities by aqueous extract of Ficus thonningii leaves on blood cells were studied in acetaminophen treated rats. The extract was safe at limit dose of 5000 mg kg-1body weight. The extract demonstrated dose dependent antihemolytic effect at dose levels between 50 and 200 m...
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