As in the adult with acute lung injury and acute respiratory distress syndrome, the use of lung-protective ventilation has improved outcomes for neonatal lung diseases. Animal models of neonatal respiratory distress syndrome and congenital diaphragmatic hernia have provided evidence that ‘gentle ventilation’ with low tidal volumes and ‘open-lung’ strategies of using positive end-expiratory pres...

INTRODUCTION Preterm birth is the most important univariant risk factor of neonatal mortality. Assessment of risk factors affecting mortality in preterm infants with very low birth weight is important for the treatment of this highly vulnerable population. OBJECTIVE Detection of risk factors for neonatal mortality in very low birth weight premature infants. METHODS The current study was con...

Background: Late preterm neonates may have the external appearance and behavior similar to their counterparts.However, they are susceptible to various neonatal morbidities , due to their physiological and metabolical immaturity.To assess the correlation between cord blood arterial lactate levels and base excess with the development ofrespiratory distress in late preterm neonat...

OBJECTIVE To study the relationship between SP-A2 and SP-B gene polymorphisms and respiratory distress syndrome in preterm neonates. DESIGN Cross-sectional. SETTING Neonatal intensive care unit and the Molecular Biology unit of the Chemical Pathology Department, Kasr Alainy hospital, Cairo University. PARTICIPANTS Sixty-five preterm infants with respiratory distress syndrome and 50 contro...

BACKGROUND Respiratory failure is a leading cause of neonatal mortality in the developing world. Bubble continuous positive airway pressure (bCPAP) is a safe, effective intervention for infants with respiratory distress and is widely used in developed countries. Because of its high cost, bCPAP is not widely utilized in low-resource settings. We evaluated the performance of a new bCPAP system to...

BACKGROUND AND OBJECTIVES: The utility of a lung ultrasound score (LUS) has been described in the early phases neonatal respiratory distress syndrome (RDS). We investigated as tool to monitor status preterm neonates throughout course RDS. METHODS: Preterm neonates, stratified 3 gestational age cohorts (25–27, 28–30, and 31–33 weeks), underwent at weekly intervals from birth. Clinical data, supp...