Rhabdomyolysis has been reported to be associated with hyperosmolality in diabetic ketoacidosis and non-ketotic hyperosmolal state. Whether the rhabdomyolysis was due to hyperosmolality per se or whether hyperglycaemia also played a role is not clear. We hereby report a case of cranial diabetes insipidus with hypernatraemia and hyperosmolality complicated by rhabdomyolysis. None of the known ri...

BACKGROUND The features of carotid atherosclerosis in ketosis-onset diabetes have not been investigated. Our aim was to evaluate the prevalence and clinical characteristics of carotid atherosclerosis in newly diagnosed Chinese diabetic patients with ketosis but without islet-associated autoantibodies. METHODS In total, 423 newly diagnosed Chinese patients with diabetes including 208 ketosis-o...

The syntheses of triglyceride and its precursors were increased when liver homogenates of ketotic diabetic rats were incubated with [U-14C]-glycero 3-phosphate and cofactors. Triolein sonicates produced a concentration-dependent inhibition of the synthesis of both diglyceride and triglyceride, whereas monoolein sonicates had no effect. Rat serum very low density lipoproteins, like triolein soni...

Introduction Lactic acidosis, first described by Clausen (1925), is most frequently seen accompanying hypotension and impaired tissue perfusion, but has been reported in association with many other conditions such as phenformin therapy, non-ketotic diabetic acidosis, ethanol ingestion and glycogen storage disease (Oliva, 1970; Lancet, 1973). Recently, an association was suggested between non-ke...

Habbick, B. F., McNeish, A. S., and Stephenson, J. B. P. (1971). Archives of Disease in Childhood, 46, 295. Diagnosis of ketotic hypoglycaemia of childhood. Twenty cases of ketotic hypoglycaemia have been diagnosed in one medical unit in the past 8 years. Typically the children were 'dysmature' at birth, with a history suggesting hypoglycaemia in the first 36 hours of life, and they have remain...

Idiopathic Ketotic Hypoglycemia is the most common non-iatrogenic cause of hypoglycemia in children beyond infancy. It improves with age and is rare after puberty. Early morning hypoglycemia, responding promptly to glucose, is a typical presentation. Etiology of hypoglycemia is unclear; deficiency of gluconeogenic substrate (hypoalaninemia) has been widely proposed. Idiopathic Ketotic Hypoglyce...

In four healthy cows an elevation of ketone bodies was induced by reduction of feed intake. Two cows became clearly ketotic while the other two cows showed only slight increases in ketone body concentrations in serum and milk. Acetone concentrations in exhaled breath were measured by gas chromatography combined with mass spectrometry. These values were correlated with concentrations of serum be...

Blood ketone bodies, serum insulin levels, and plasma free fatty acids were examined in a series of patients with "non-ketotic diabetic coma" and compared with the findings in ketoacidotic subjects. Serum insulin levels in six "non ketotic" patients ranged between 1 and 25 muu./ml. and were not significantly different from levels reported in patients with ketoacidosis. In addition, plasma free ...