Kawasaki disease occurs most often in children of East Asian ancestry, but the known genetic factors cannot explain why more children have been diagnosed with the disease in recent years, according to Bing-Fang Hwang, an environmental epidemiologist at China Medical University in Taiwan. Hwang and colleagues now report an association between exposure to ground-level ozone and increased risk of ...

Background—Kawasaki disease is an acute self-limited vasculitis of childhood that is characterized by fever, bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, changes in the extremities, rash, and cervical lymphadenopathy. Coronary artery aneurysms or ectasia develop in 15% to 25% of untreated children and may lead to ischemic heart disease or sudden death. Methods an...

BACKGROUND Kawasaki disease results from an abnormal immunological response to one or more infectious triggers. We hypothesised that heritable differences in immune responses in Kawasaki disease-affected children and their families would result in different epidemiological patterns of other immune-related conditions. We investigated whether hospitalisation for infection and asthma/allergy were ...

Kawasaki disease is an acute vasculitis of childhood that predominantly affects the coronary arteries. The etiology of Kawasaki disease remains unknown, although an infectious agent is strongly suspected based on clinical and epidemiologic features. A genetic predisposition is also likely, based on varying incidences among ethnic groups, with higher rates in Asians. Symptoms include fever, conj...

Kawasaki disease is a multi system disorder with varying clinical expressions. This disease is an acute systemic vasculitis of unknown etiology that has recently recognized as a leading cause of acquired heart disease in children of many developed countries. We describe an unusual instance of hair loss in a patient with Kawasaki disease. A 26 months old boy developed prolonged high fever, bilat...

Kawasaki disease was first described by Dr. Tomisaku Kawasaki in 1967. This disease is an acute, febrile illness primarily affecting infants and children younger than 4 years old. Although this disease is characterized by systemic vasculitis, the etiology is still unknown. To clarify the epidemiologic features of Kawasaki disease, nationwide surveys have been conducted since 1970. Approximately...

The damage spreading of the Ising model on several two-dimensional trivalent structures, including soap froth, Voronoi, and hierarchical structures, are studied with competing Glauber and Kawasaki dynamics. The damage spreading transition temperature T(d) and the Curie temperature T(C) of these structures are compared. We find that T(d) of the hierarchical lattices decreases sharply as the prob...

BACKGROUND AND PURPOSE Kawasaki disease is a febrile disease of children notable for systemic vasculitis. There have been many previous reports of various complications, including disorders of the central nervous system. We evaluated cerebral perfusion during the acute stage in patients with Kawasaki disease. METHODS Single-photon emission-computed tomography (SPECT) with 99mTc-hexamethylprop...

INTRODUCTION Kawasaki disease is an idiopathic acute systemic vasculitis of childhood. Although it simulates the clinical features of many infectious diseases, an infectious etiology has not been established. This is the first reported case of Kawasaki disease following Rocky Mountain spotted fever. CASE PRESENTATION We report the case of a 4-year-old girl who presented with fever and petechi...