CC: calcinosis cutis DLE: discoid lupus erythematosus SLE: systemic lupus erythematosus INTRODUCTION Calcinosis cutis (CC) is a rare disorder known to occur commonly in association with underlying autoimmune connective tissue diseases. CC primarily occurs in patients with dermatomyositis, systemic scleroderma, and mixed connective tissue disease. It is only rarely associated with systemic lupus...

Macrophage activation syndrome (MAS) is a severe, potentially fatal condition that may complicate autoimmune diseases, and it belongs to hemophagocytic lymphohistiocytosis (HLH) disorders. MAS occurs in adults and children. However, it is rare in juvenile systemic lupus erythematosus (jSLE), and it is extremely rare to be the initial presentation of jSLE. Here, we report two patients with juven...

Macrophage activation syndrome (MAS) is a life-threatening complication in juvenile systemic lupus erythematosus(J SLE). We report three cases of MAS in Juvenile SLE which occurred over the last 6 months. Interestingly, in all the 3 cases, MAS occurred acutely at the time of first presentation of lupus. All of them had fever at presentation. Two of them had lymphadenopathy and splenomegaly and ...

OBJECTIVE To demonstrate the role of sonography in depicting periarticular changes in juvenile systemic lupus erythematosus (SLE) and to find out whether certain tendons in juvenile SLE patients were different from those of healthy controls. METHODS Thirty juvenile SLE patients (27 female, 3 male) were recruited for this study. Sonographic evaluations were performed in the knee, ankle, elbow,...

CLE: cutaneous lupus erythematosus HZ: herpes zoster SLE: systemic lupus erythematosus TLE: tumid lupus erythematosus VZV: varicella zoster virus INTRODUCTION Topical corticosteroids are commonly used in the treatment of a wide range of skin manifestations of systemic lupus erythematosus (SLE). Patients with SLE are also known to have an increased risk of herpes zoster (HZ). Here we present a r...

OBJECTIVE The goal of the present study was to estimate the risk ratio of herpes zoster among systemic lupus erythematosus patients after disease onset compared with a cohort of patients without systemic lupus erythematosus over a three-year period. METHODS A nationwide population-based cohort study using the National Health Insurance Research Database identified 10,337 new cases of systemic ...