We thank Drs Myrianthefs and Baltopoulos for the data reported in their letter. They used the results of our recently published study in CHEST 1 to evaluate the different economic outcomes of patients in the ICU with ventilator-associated pneumonia (VAP) treated with IV colistin monotherapy or aerosolized plus IV (AS 1 IV) colistin therapy in a Greek hospital. They found that 7-day AS 1 IV coli...

social phobia is one of the anxiety disorders. the people wit h social phobia fear social situations and they are afraid to meet and talk with others and try avoid social situations .social phobia influence on academic and occupational function. many researches have confirmed the effect of family therapy based on cognigive-behavioral approach on social phobia. the main purpose of the present re...

background: in patients with acute ischemic cerebral infarction, thrombolytic therapy using intravenous tissue plasminogen activator (iv?tpa) necessitates precise documentation of symptoms’ onset. the aim of this study was to identify major barriers related to the iv?tpa injection in such patients. materials and methods: between 2014 and 2015, patients with definitive diagnosis of acute cerebra...

Lyme arthritis, caused by the tick-borne spirochete Borrelia burgdorferi (1), typically causes intermittent or persistent arthritis in a few large joints, especially the knee, for several years (2). Treatment recommendations have changed over time. In the early 1980s, 3 intramuscular injections of benzathine penicillin or a 10-day course of high-dose intravenous (IV) penicillin cured only 35–55...

OBJECTIVE To evaluate the effectiveness of guanfacine extended-release (GXR) versus placebo as adjunct therapy to usual care stimulant therapy in improving executive function in children aged 6 to 12 years diagnosed with ADHD. METHOD In this single center, double-blind placebo-controlled crossover trial, subjects continued to take their psychostimulant and were randomly assigned at baseline t...