OBJECTIVE It is standard practice to clean the skin using a non-alcohol-containing swab before forensic blood alcohol sampling, because of the belief that the use of an alcohol-containing swab will contaminate the sample. The present study aimed to determine whether cleaning the skin with 70% isopropyl alcohol swabs, before venepuncture, alters measured blood alcohol level (BAL). METHODS Volu...

The title compound, C(20)H(26)O(7), was prepared by esterification of 2,3;5,6-di-O-isopropyl-idene-α-d-mannofuran-ose with phenyl-acetic acid under standard DCC/DMAP (DCC = dicyclohexylcarbodiimide and DMAP = 4-dimethylaminopyridine) con-ditions. The solid-state structure confirms the retention of the α-configuration at the anomeric C atom. The compound is characterized by a relatively rigid fr...

Several mouse aldehyde dehydrogenases catalyze the detoxification of aldophosphamide, the pivotal metabolite of the prodrugs cyclophosphamide, mafosfamide, and other oxazaphosphorines. N-Isopropyl-p-formylbenzamide, a major metabolite of procarbazine, was found to be an excellent substrate (Km = 0.84 microM) for at least one of these enzymes, namely, mouse aldehyde dehydrogenase-2. The Km for m...

The aim of this study was to optimize topical nanoemulsions containing genistein, by means of a 23 full factorial design based on physicochemical properties and skin retention. The experimental arrangement was constructed using oil type (isopropyl myristate or castor oil), phospholipid type (distearoylphosphatidylcholine [DSPC] or dioleylphosphaditylcholine [DOPC]), and ionic cosurfactant type ...

BACKGROUND Terra-firma forme dermatosis, also known as Duncan's dirty dermatosis, is a benign skin condition that presents as dirt-like plaques in patients of all ages. PURPOSE We describe a series of ten patients that presented with terra-firma forme dermatosis. METHODS AND MATERIALS We reviewed PubMed for the following terms: dermatosis, Duncan's dirty dermatosis, isopropyl alcohol, terra...

We read with interest the recent article by Batalla et al. on the use of hand hygiene and antisepsis products among health care professionals and the relationship between these products and hand eczema. While we are in full agreement with the central message of the article and the authors’ algorithm for the management of patients with intolerance to alcohol-based products, we would like to add ...

NUMBER 1, SEPTEMBER, 1946 I. The Response of Hypodynamic Myocardium to Known Concentrations of Cardiac Glycosides. Wallace F. White and William T. Salter 1 II. Comparison of Pressor Action of Aliphatic Amines. E. E. Swanson and K. K. Chen 10 III. Digitalis. III. The Relationship Between the Potency and Baljet Reaction of the Glycosides of Digitalis. Frederick K. Bell and John C. Krantz, Jr 14 I...

BACKGROUND Many disinfectants have been used clinically in both single and combination applications, but there have been few studies on disinfective power according to sterilization sequence when using a combination of disinfectants. The purpose of this study was to evaluate the disinfective power of a combination of 70% isopropyl alcohol and 10% povidone-iodine (PVP-I) according to sterilizati...