This work was undertaken to study the mechanical factors affecting the function of the isolated heart of Helix pomatia in order to help understand the variations in heart activity observed in intact animals. Biedermann (1884), working upon the isolated heart of Helix, observed that the frequency of beat increased with distension of the heart. Biering (1929) found that in the isolated Helix hear...

abstract introduction: resent studies have been shown beneficial effects of hyperoxia pretreatment against ischemia-reperfusion injury in different organs. the aim of the present study was to investigate early and late effects of normobaric hyperoxia (≥95% o2) pretreatment on ischemia-reperfusion injuries in isolated rat hearts. methods: following 60 and 180 minutes of hyperoxia, rat hearts wer...