background & aim: stroke in young adults is rare but can be devastating for the affected individuals and their families. some triggers of stroke may be acute but transient effects on the pathophysiological condition while other factors may be effective overa longer period. methods & materials: this study was a case-crossover study on 18 young adults. the study included patients aged 15-49 years...

Myxoma may cause systemic embolization and frequently presents as ischemic stroke. There has been debates whether it is safe to use recombinant tissue plasminogen activator (rt-PA) in patients with cardiac myxoma who are presented with ischemic stroke at emergency department. we describe a young case of atrial myxoma with initial presentation of acute cerebral infarction symptoms who was treate...

Arterial ischemic stroke (AIS) in adults is considered a serious health threat and requires urgent medical treatment. Prompt diagnosis allows the therapeutic option of thrombolysis within the time window of 3 to 6 hours after first symptoms. Alternatively, early anti-platelet therapy is effective in improving the outcome after stroke. The incidence of pediatric AIS range from 2 to 5 per 100 000...

Introduction: Arterial hypertension is one of the causes of stroke, and as one of the vasculotoxic conditions intensifies ischemic stroke complications. The aim of the present study was to analyze the effects of short-term cerebral hypertension on ischemia/reperfusion injury and pathogenesis of ischemic stroke. Methods: The experiments were performed on three groups of rats (N=36) Sham, cont...

background: stroke is a multifactorial disorder, the most common cause being arterial occlusion. transcranial doppler ultrasonography (tcd) is a common non-invasive method available for assessment the arterial blood flow of the brain. objective: assessment the hemodynamic parameters of cerebral arteries, using tcd device in patients suffering ischemic stroke. materials and methods: this descrip...

Ischemic stroke has been classified as a merely thrombotic disease, so the main goal of its treatment is the recanalization of the occluded vasculature. However, despite fast restoration of blood circulation, progressive stroke still develops in many patients, which has led to the concept of reperfusion injury.  The underlying mechanism is only partly known. Though, it is accepted now, tha...

background: numerous studies have evaluated the association between the angiotensinogen (agt) t174m polymorphism and ischemic stroke(is) risk. however, the specific association is still controversial. materials and methods: in order to explore this association more deeply, we performed a meta-analysis. all of the relevant studies were identified from pubmed, embase, and chinese national knowled...

background: the aim of this study is to determine the frequency of intracranial artery stenosis in patients with acute ischemic stroke in iran. methods: a total of 169 patients with acute ischemic stroke were eligible to participate and were enrolled in this study from january 2012 to february 2013. all the patients were admitted to the nemazee ‎hospital, affiliated to shiraz university of medi...

Background: Patients with ischemic stroke and underlying Atrial Fibrillation (AF) have a high risk of recurrent embolic events. New Oral Anticoagulant (NOAC) is highly effective and reduces the risk of recurrence in AF-associated Ischemic Stroke (AFAIS). Objectives: This study aimed to determine the prescription pattern of NOAC and its determinant factors in patients with non-valvular AFAIS. ...