Introduction: Brachytherapy, especially using manually after loaded Iridium-192 and Cobalt-60, can be applied as a sole treatment, as a treatment complementary to surgery, and as a local boost in combination with EBRT. The use of HDR brachytherapy catheters incorporated in removable dental molds allows repeated, highly reproducible, fractionated outpatient brachytherapy of supe...

Biscyclometalated iridium(III) complexes with an ancillary acetylacetone ligand, Ir(L)(2)(acac), (L = 2-(benzo[b]thiophen-2-yl)pyridine (btp), 1-phenylisoquinoline (piq), 2-phenylbenzothiazole (bt), 2-phenylpyridine (ppy), acac = deprotonated acetylacetone), demonstrate spectroscopic changes in their UV-Vis absorption and luminescent emission under acidic conditions. Such changes were found to ...

Cyclometalated iridium complexes have important applications as phosphorescent probes for cellular imaging due to their photophysical properties. Moreover, these properties also make them potential candidates as photosensitizers for photodynamic therapy (PDT) of tumors and skin diseases. Treatment of MCF7 breast carcinoma cells with a heteroleptic phosphorescent cyclometalated iridium(III) comp...

Needle-shaped crystals of the metal-rich phosphide Ce4Ir13.55P9 were synthesized from the elements in a lead flux (starting composition 1 : 2 : 2 : 60) at 1370 K followed by slow cooling. Ce4Ir13.55P9 crystallizes with a new orthorhombic structure type: Pnma, a = 1269.1(2), b = 399.1(1), c = 3349.9(7) pm, wR2 = 0.0722, 2025 F2 values and 139 variables. Two of the 14 crystallographic iridium sit...

The Birkeland currents, J‖, electrically couple the high latitude ionosphere with the near Earth space environment. Approximating the spatial distribution of the Birkeland currents may be achieved using the divergence of the ionospheric electric field, E⊥, assuming zero conductance gradients such that J‖≈6p∇·E⊥. In this paper, electric field data derived from the Super Dual Auroral Radar Networ...

OBJECTIVE Vagal nerve stimulation (VNS) has shown potential benefits for obesity treatment; however, current devices lack physiological feedback, which limit their efficacy. Changes in extracellular pH (pHe) have shown to be correlated with neural activity, but have traditionally been measured with glass microelectrodes, which limit their in vivo applicability. APPROACH Iridium oxide has prev...

Two azacrown ether appended iridium(III) complexes, 1 and 3, are described as probes for metal cations operating on oxidative-reduction electrochemiluminescence (ECL) with tri-n-propylamine as coreactant in acetonitrile. Complexes 1 and 3 exhibit a notable ECL sensing for Ba(2+) and Ag(+), respectively, through a 9-fold emission intensity enhancement and an unprecedented λmax(em) red shift. In ...

PURPOSE This multicenter, retrospective study evaluated treatment and clinical outcomes of patients with early stage breast cancer who received adjuvant high-dose rate (HDR) electronic brachytherapy (EBT) treatment post-lumpectomy using the Axxent(®) EBT system. Dosimetric data from the EBT treatment plans were compared with those based on iridium-192 HDR brachytherapy. MATERIAL AND METHODS M...

Potential dual-mode monopropellant/electrospray capable binary mixtures of hydroxyl ammonium nitrate with ionic liquid fuels [Bmim][NO3] and [Emim][EtSO4] are synthesized and tested for monopropellant ignition capability in a micro reactor setup. The setup is benchmarked using 30% hydrogen peroxide solution decomposed via silver catalyst. Results show similar trends, but variance in the quantit...