نتایج جستجو برای: ion concentrations
تعداد نتایج: 498727 فیلتر نتایج به سال:
Hofmeister (ion specic) effects are phenomena related to the chemical nature of electrolytes. Although they are ubiquitous in all chemical, colloidal, and biological systems, they cannot be quantied in terms of the conventional physico-chemical theories (i.e. Debye–Hückel, DLVO, etc.). These are limit theories, based on electrostatics, and valid at innite dilution only. The gap between theor...
To understand the mechanisms of Na(+)/Li(+) permeation at submicromolar Ca(2+) concentrations, Na(+)/Li(+) blocking at higher Ca(2+) concentrations (10(-6)-10(-4) M) and Ca(2+) permeation at millimolar Ca(2+) concentrations, we used our recently described L-type calcium channel model. For this purpose, we obtained potential of mean force (pmf) curves for the position change of one Na(+) and one...
General anesthetics have revolutionized medicine by facilitating invasive procedures, and have thus become essential drugs. However, detailed understanding of their molecular mechanisms remains elusive. A mechanism proposed over a century ago involving unspecified interactions with the lipid bilayer known as the unitary lipid-based hypothesis of anesthetic action, has been challenged by evidenc...
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