نتایج جستجو برای: iohexol
تعداد نتایج: 541 فیلتر نتایج به سال:
IntroductionOne-quarter of adults worldwide fulfill the criteria metabolic syndrome (MetS). MetS increases risk diabetes, chronic kidney disease (CKD), and cardiovascular disease. However, association between MetS, hyperfiltration, long-term GFR decline in general population is unknown.MethodsIn Renal Iohexol Clearance Survey (RENIS), we investigated 1551 people aged 50-63 years, representative...
In this study, X-ray computed tomography (CT) was utilized as a noninvasive method to directly examine local drug release kinetics in livers before and following radiofrequency thermal ablation. Iohexol, a CT contrast agent, was used as a drug-mimicking molecule. Release of iohexol in healthy and ablated rabbit livers over 48 h was quantified and correlated with the release profiles from phosph...
Contrast-induced acute kidney injury (CIAKI) is a leading cause of acute kidney injury following radiographic procedures. Intrarenal oxidative stress plays a critical role in CIAKI. Nicotinamide adenine dinucleotide 3-phosphate (NADPH) oxidases (Noxs) are important sources of reactive oxygen species (ROS). Among the various types of Noxs, Nox4 is expressed predominantly in the kidney in rodents...
BACKGROUND Identifying methods to accurately measure the glomerular filtration rate (GFR) in obese individuals without kidney overt kidney disease is necessary to understanding the pathophysiology and natural history of obesity-related kidney disease. METHODS Using a cross-sectional design, iohexol clearance and disposition was measured, an optimal sampling schedule was identified, and the re...
We compared the Swedish Coronary Angiography and Angioplasty Registry with the Swedish 'Hospital Discharge Register' to assess contrast media (CM)-induced renal failure. Hospitals used only one type CM. From 2000 to 2003, iodixanol (iso-osmolar) was used in 45 485 patients, ioxaglate (low osmolar) in 12 440 subjects. To include the earlier used CM iohexol (low osmolar), analysis extended back t...
In vivo release profiles of drug-loaded biodegradable implants were noninvasively monitored and characterized using X-ray computed tomography (CT). The imaging method was adapted and optimized to quantitatively examine the release of an active agent from a model cylindrical PLGA device (the millirod) into rabbit livers over 48 h. Iohexol, a CT contrast agent, served as a model drug; optimizatio...
We investigated the optimal method of administering iohexol, which contains 300 mg iodine/ml (Omnipaque 300), a nonionic contrast medium, to maintain adequate renal contrast while reducing artifacts during dynamic CT scanning. In this study, 76 patients with renal disease received 10-50 ml of iohexol as follows: group I (14 patients), 20 ml injected as an intravenous bolus for 5 sec, followed b...
Owing to their high consumption for X-ray diagnose and rapid excretion from organism, iodinated contrast media (ICM) are often found in source waters. It is a serious public health concern due potential generate highly toxic disinfection by-products. Reductive deiodination of ICM considered as promising approach degrade them allows the possible recovery iodide ions. Electrocatalytic reduction i...
4 ORIGINAL PAPERS 5 ABBREVIATIONS 6 INTRODUCTION 7 Marker substances for GFR 8 Endogenous markers 8 Exogenous markers 8 Clearance techniques for determination of GFR 9 Continuous infusion method 9 Single injection method 10 Single injection, single sample methods 12 AIMS OF THE STUDY 16 MATERIALS AND METHODS 17 Materials 17 Cr-EDTA and Tc-DTPA analysis 18 Iohexol analysis 19 Derivation of a sin...
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