نتایج جستجو برای: invariant nkt cells

تعداد نتایج: 1456579  

Journal: :The Journal of Experimental Medicine 2003
Madhav V. Dhodapkar Matthew D. Geller David H. Chang Kanako Shimizu Shin-Ichiro Fujii Kavita M. Dhodapkar Joseph Krasovsky

We studied the function of antitumor T and natural killer T (NKT) cells from the blood and tumor bed in 23 patients with premalignant gammopathy, nonprogressive myeloma, or progressive multiple myeloma. We show that antitumor killer T cells can be detected in patients with both progressive or nonprogressive myeloma. V alpha 24+V beta 11+ invariant NKT cells are detectable in the blood and tumor...

Journal: :Experimental and Molecular Medicine 2009

Journal: :Proceedings of the National Academy of Sciences 2009

Journal: :Journal of immunology 2014
Igor Maricic Enrico Girardi Dirk M Zajonc Vipin Kumar

Lipids presented by the MHC class I-like molecule, CD1d, are recognized by NK T (NKT) cells, which can be broadly categorized into two subsets. The well-characterized type I NKT cells express a semi-invariant TCR and can recognize both α- and β-linked glycolipids, whereas type II NKT cells are less well studied, express a relatively diverse TCR repertoire, and recognize β-linked lipids. Recent ...

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