An introduction to the thematic section by guest editors Diana Gonçalves Vidal and Naomar de Almeida-Filho.

Suppose that after a lengthy computation the computer gives you some real number, and you want to be sure that this number is the correct result, or at least close to it. Or you need to know whether the problem (a nonlinear system, a differential equation, etc.) has a solution at all and where the solution(s) may be, or how much the results can vary if there are tolerances in the input. In this...

Molecular Probes provides a full spectrum of fluorophores and haptens for labeling biopolymers and derivatizing low molecular weight molecules. Chapters 1–5 describe the chemical and spectral properties of the reactive reagents we offer, whereas the remainder of this Handbook is primarily devoted to our diverse collection of fluorescent probes and their applications in cell biology, immunology,...