PURPOSE To investigate the effect of bevacizumab (Avastin; Genentech, San Francisco, CA, USA) on vascular endothelial growth factor (VEGF) expression and inflammation in fibrovascular membranes in patients with proliferative diabetic retinopathy (PDR). MATERIALS AND METHODS Fibrovascular membranes from 19 eyes of 18 patients with PDR were studied using immunohistochemistry and analyzed in the...

PURPOSE To compare the pharmacokinetics and tissue response between intravitreal and microcannulation injections into the suprachoroidal space using bevacizumab. METHODS Sixty-two pigs were studied. Either a pars plana intravitreal bevacizumab or a viscoelastic-enhanced microcannula suprachoroidal injection was performed with either 1.25 mg (group 1) or 3 mg (group 2). In group 1, six animals...

purpose: one of the major causes of visual acuity loss in diabetic patients is diabetic macular edema (dme). best-corrected visual acuity and central macular thickness changes are considered as two main outcomes in diabetic macular patients. the goal of this study was to compare the effect of intravitreal bevacizumab injection alone or combined with triamcinolone versus macular photocoagulation...

800x600 to report the efficacy of combination therapy (bevacizumab and photocoagulation) in a case of eales disease this study has been performed. bevacizumab (avastin, 1.25 mg/0.05 ml) was injected intravitreously for the treatment of iris and retinal neovascularization in a 56-year old hispanic female with photocoagulation treatment to control the recurrence of vitreous haemorrhage. our resul...

purpose: to study the effects of adding intravitreal bevacizumab (avastin) to conventional laser treatment on regression of retinal neovascularization in threshold rop. methods: intravitreal injection of bevacizumab (1.25 mg) in one eye of each of three newborns with threshold rop was performed in addition to laser treatment. the other eye of each patient was treated with laser alone. changes i...

OBJECTIVE To compare the efficacy of intravitreal bevacizumab and ranibizumab for the treatment of neovascular age-related macular degeneration using an as-needed treatment regimen. DESIGN Retrospective chart review. PARTICIPANTS One hundred and ninety two eyes of 184 patients. METHODS Patients received an initial treatment of 3 monthly intravitreal injections of ranibizumab or bevacizuma...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : diabetic macular edema (dme) is the most common cause of reduced vision in diabetic patients. with regards to its prevalence and its severe morbidity, attention to new methods of treatment like anti-vascular endothelial growth factor (vegf) therapy is of great importance. therefore, this study aimed to evaluat...

purpose: to evaluate the effect of intravitreal bevacizumab (ivb) injection on sustained intraocular pressure (iop) methods: this non-randomized prospective study was conducted on 359 eyes of 359 patients in amir almomenin (rasht) and labbafinejad (tehran) hospitals. after history taking and complete ocular examination, iop was measured one week and one day before injection (twice at each sessi...

Objectives: The aim of this study is to investigate the effect preoperative intravitreal Bevacizumab on postoperative incidence vitreous cavity hemorrhage in patients with advance diabetic eye disease undergoing 23 gauge pars plana vitrectomy. Study Duration: This was conducted department Ophthalmology Services Hospital Lahore from April 2021 September 2021. Design: Randomized Controlled Trail ...

PURPOSE To demonstrate the role of intravitreal bevacizumab in regression of iris neovascularization, and intraocular pressure (IOP) control in neovascular glaucoma. METHODS A retrospective random case series study was performed. Twenty eyes of 20 patients who presented with neovascular glaucoma were treated with intravitreal bevacizumab 2.5 mg in 0.1 mL. Retinal photocoagulation was performe...