The hospital is a health facility that provides diagnostic and therapeutic services to patients for various diseases mental problems, both surgical non-surgical. It place get healing an illness suffered. At present medical devices need attention the right results when treating patients, of course, increasing technological sophistication. One common procedures performed on administer drugs via i...

In view of the results of animal studies as well as theoretical considerations, continuous administration of beta-lactam antibiotics should be superior to intermittent administration because of the close relationship between efficacy and the duration of time in which the concentration of unbound antibiotics in plasma remains above the MIC. The aim of the present study was to establish the pharm...

BACKGROUND Endostatin is an endogenous collagen XVIII-fragment with anti-angiogenic properties and remarkable antitumor activity in mice. Preclinical data suggest that continuous low dose administration of endostatin is much more potent than intermittent dosing. The feasibility of this approach is tested in a phase I study. PATIENTS AND METHODS We determined the safety and pharmacokinetic pro...

Retrospective cohort study. Data was collected from medical records June 2018 to September 2019 for consecutive patients aged 18 and older undergoing elective laparoscopic sleeve gastrectomy obesity. A standardized ERAS pathway bariatric surgery utilized in all study patients. For anesthetic maintenance, the OFA group (n = 46) received propofol combined with dexmedetomidine, lidocaine, and/or k...

CLINICAL PHARMACOLOGY Adults Peak plasma concentrations of piperacillin and tazobactam are attained immediately after completion of an intravenous infusion of Piperacillin and Tazobactam for Injection. Piperacillin plasma concentrations, following a 30 minute infusion of Piperacillin and Tazobactam for Injection, were similar to those attained when equivalent doses of piperacillin were administ...

A study was carried out in which patients were asked questions to assess their knowledge of their condition and treatment, the questions relating particularly to care before siting an intravenous infusion and preoperative care. A high proportion of patients knew little about the procedure they were about to undergo. It is recommended that patients should be told more about matters relating to t...

Biliary excretion of platinum was measured in a patient receiving an intravenous infusion of cis-dichlorodiammineplatinum (II). Over a 3-day period, less than 1% of the administered platinum was detected in the bile, and 47% appeared in the urine, indicating that biliary excretion is a minor route of elimination.

In an earlier trial [7, 11] with intravenously administered PGF2# for the elective induction of multiparae at term, amniotomy was delayed to comply with FD A regulations. As a consequence, the Start of the electronic supervision was also postponed and thus the refined ässessment of the potential fetal ha2ards of PGF2& was prevented. The present study was tailored in accordance with the dual pur...

Attempts were made to control prolonged seizures with rapid intravenous administration of either diazepam or methohexitone in relatively small doses under electroencephalographic (EEG) monitoring. The clinical and EEG features are discussed in relation to 65 episodes which occurred in 51 infants and children. Both clinical and EEG effects may become apparent in half a minute when the drug is ad...

The pharmacokinetics of ofloxacin were investigated in eight healthy male volunteers. A single infusion (200 mg over 0.5 h) was performed on day 1, followed by a washout period of 2 weeks. Repeated administrations were performed for 4 days (200 mg every 12 h). Pharmacokinetic parameters were determined from the plasma decay curves of the single and the last of the multiple administrations. Oflo...