Increasing use of short-course antifungal therapies in patients with recurrent vulvovaginitis may enable the emergence of less-common, more resistant yeast strains as vaginal pathogens. We report the case of a patient with chronically symptomatic and repeatedly treated vaginal candidiasis whose infection was attributable to Candida lusitaniae, a previously unreported cause of candidal vaginitis.

IntroductionThe range of potential complications due to the long-term presence a foreign body in vagina is extremely wide, while treatment some, requires extensive and mutilating surgical interventions.Case reportA 19-year-old patient sought medical attention because incontinence. Historically, states that 3.5 years ago, state impaired judgment during sexual intercourse, cork from bottle hairsp...

BACKGROUND To assess the efficacy of luteal phase support (LPS) using intravaginal progesterone (P) on pregnancy rate in Iranian women with polycystic ovarian syndrome (PCOS) who used a combination for ovulation induction consisting of letrozole or clomi- phene citrate (CC) and human menopausal gonadotropin (HMG). MATERIALS AND METHODS This was a randomized clinical trial undertaken in a fert...

BACKGROUND This is a Phase I trial demonstrating safety and tolerability of intravaginal curcumin for future use in women with cervical neoplasia. OBJECTIVE The objective of this study was to assess the safety, tolerability, and pharmacokinetics of intravaginal curcumin in healthy women. STUDY DESIGN We conducted a 3+3 dose-escalation Phase I trial in a group of women aged 18-45 years. Thir...

In the present study we investigate the impact of a range of TLR ligands and chitosan as potential adjuvants for different routes of mucosal immunisation (sublingual (SL), intranasal (IN), intravaginal (IVag) and a parenteral route (subcutaneous (SC)) in the murine model. We assess their ability to enhance antibody responses to HIV-1 CN54gp140 (gp140) and Tetanus toxoid (TT) in systemic and vag...

BACKGROUND Intravaginal practices may affect the colonization of vaginal flora and lead to vaginal infections due to the potential effects on the vaginal environment. This study investigated the vaginal practices and their possible effects on vaginal lactobacilli flora colonization in women in Accra. METHODS A cross-sectional, descriptive single-site study was carried out on 141 women assessi...