Intratympanic dexamethasone (IT-DEX) injection is a useful treatment option for patients that fail systemic steroid therapy for treatment of sudden idiopathic sensorineural hearing loss (SSNHL). The clinical results of patients with SSNHL treated with IT-DEX are not always consistent with the apical-basal gradient pattern of concentration, even though it has been generally known that the treatm...

In this report, we summarize our clinical experience with intratympanic dexamethasone treatment (IDT) for control of tinnitus. From March 2000 through February 2001, we observed 54 patients (23 women, 31 men; mean age, 49.6 +/- 7.2 years; range, 24-71 years) suffering from subjective idiopathic tinnitus (SIT). After common audiological tests had been performed; all patients underwent specific t...

Over the last 6 months, all patients seen at the otologic clinic of Brasília University Medical School answered a questionnaire designed to identify and describe the symptom of tinnitus. A total of 500 patients reported and described this symptom. They underwent physical examination, laboratory tests and audiological evaluation. In their order of frequency, presbycusis, chronic otitis media, ot...

OBJECTIVES To evaluate the hearing outcomes of intratympanic steroid (ITS) treatment for patients with acute low-tone sensorineural hearing loss (ALHL) after failure of initial therapy and to investigate the recurrence and progression to definite Ménière's disease (MD) during a long-term follow-up. METHODS We retrospectively reviewed the medical records of 90 patients with refractory ALHL who...

Data Sources: An electronic database search (MEDLINE and PubMed) was performed with the objective of identifying all studies published in the English language between January 1980 and October 2014 on the treatment of intratympanic methylprednisolone injection in ISSNHL. Prospective, non-randomized, case review of patients diagnosed with ISSNHL treated with intratympanic methylprednisolone from ...